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Association between MEG3/miR-181b polymorphisms and risk of ischemic stroke.

Xuemei Han | Zhaoshi Zheng | Chunhui Wang | Libo Wang
Lipids in health and disease | 2018

Recent evidence suggests that long non-coding RNAs (lncRNAs) are key regulators in the pathological process of ischemic stroke (IS). Maternally expressed gene 3 (MEG3) was observed to be up-regulated in IS, acting as a competing endogenous RNA for miR-181b to regulate ischemic brain injury. The purpose of this study was to evaluate the association of tagSNPs in MEG3 (i.e., rs7158663 and rs4081134) and miR-181b rs322931 with IS risk.

Pubmed ID: 30579356

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