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Discontinuation of tyrosine kinase inhibitors in CML patients in real-world clinical practice at a single institution.

Nuno Cerveira | Bruno Loureiro | Susana Bizarro | Cecília Correia | Lurdes Torres | Susana Lisboa | Joana Vieira | Rui Santos | Dulcineia Pereira | Cláudia Moreira | Sérgio Chacim | Nélson Domingues | Ana Espírito-Santo | Isabel Oliveira | Ilídia Moreira | Luísa Viterbo | Ângelo Martins | Manuel R Teixeira | José M Mariz
BMC cancer | 2018

Most patients with chronic myeloid leukemia (CML) treated with tyrosine kinase inhibitors (TKIs) will relapse if treatment is withdrawn, but various trials have recently demonstrated that a significant proportion of patients who achieved a stable and deep molecular response (DMR) can stop therapy without relapsing. However, most information on treatment cessation was obtained from clinical trials with strict recruiting criteria.

Pubmed ID: 30541488

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SPSS (tool)

RRID:SCR_002865

Software package used for interactive, or batched, statistical analysis in social science, health sciences and marketing. Software platform offers advanced statistical analysis, a library of machine-learning algorithms, text analysis, open-source extensibility, integration with big data and deployment into applications.Versions that were produced by SPSS Inc. before the IBM acquisition (Versions 18 and earlier) would be given origin or publisher of SPSS Inc. in Chicago.

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