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Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression.

Åsmund T Røe | Marianne Ruud | Emil K Espe | Ornella Manfra | Stefano Longobardi | Jan M Aronsen | Einar Sjaastad Nordén | Trygve Husebye | Terje R S Kolstad | Alessandro Cataliotti | Geir Christensen | Ole M Sejersted | Steven A Niederer | Geir Øystein Andersen | Ivar Sjaastad | William E Louch
Cardiovascular research | 2019

Regional heterogeneities in contraction contribute to heart failure with reduced ejection fraction (HFrEF). We aimed to determine whether regional changes in myocardial relaxation similarly contribute to diastolic dysfunction in post-infarction HFrEF, and to elucidate the underlying mechanisms.

Pubmed ID: 30351410

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QIAGEN (tool)

RRID:SCR_008539

A commercial organization which provides assay technologies to isolate DNA, RNA, and proteins from any biological sample. Assay technologies are then used to make specific target biomolecules, such as the DNA of a specific virus, visible for subsequent analysis.

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WI (tool)

RRID:RGD_13508588

Rattus norvegicus with name WI from RGD.

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