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Publication

Heterogeneity in association of remote herpesvirus infections and pediatric MS.

Bardia Nourbakhsh | Alice Rutatangwa | Michael Waltz | Mary Rensel | Manikum Moodley | Jennifer Graves | Theron Charles Casper | Amy Waldman | Anita Belman | Benjamin Greenberg | Manu Goyal | Yolanda Harris | Ilana Kahn | Timothy Lotze | Soe Mar | Teri Schreiner | Gregory Aaen | Janace Hart | Jayne Ness | Jennifer Rubin | Jan-Mendelt Tillema | Lauren Krupp | Mark Gorman | Leslie Benson | Moses Rodriguez | Tanuja Chitnis | John Rose | Meghan Candee | Bianca Weinstock-Guttman | Xiaorong Shao | Lisa Barcellos | Judith James | Emmanuelle Waubant | US Network of Pediatric MS Centers
Annals of clinical and translational neurology | 2018

While prior Epstein-Barr virus (EBV) infection has been consistently associated with subsequent risk of developing multiple sclerosis (MS), the association with other common herpesviruses has been more controversial. Our objectives were to determine whether remote infection with EBV and other common herpesviruses affect the susceptibility to pediatric MS and if there are interactions between genetic and demographic factors and viral infections.

Pubmed ID: 30349857

Research resources used in this publication

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Associated grants

  • Agency: NINDS NIH HHS, United States
    Id: R01 NS071463
  • Agency: NIGMS NIH HHS, United States
    Id: U54 GM104938
  • Agency: NCATS NIH HHS, United States
    Id: UL1 TR002538

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PLINK (tool)

RRID:SCR_001757

Open source whole genome association analysis toolset, designed to perform range of basic, large scale analyses in computationally efficient manner. Used for analysis of genotype/phenotype data. Through integration with gPLINK and Haploview, there is some support for subsequent visualization, annotation and storage of results. PLINK 1.9 is improved and second generation of the software.

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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