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Language delay aggregates in toddler siblings of children with autism spectrum disorder.

N Marrus | L P Hall | S J Paterson | J T Elison | J J Wolff | M R Swanson | J Parish-Morris | A T Eggebrecht | J R Pruett | H C Hazlett | L Zwaigenbaum | S Dager | A M Estes | R T Schultz | K N Botteron | J Piven | J N Constantino | IBIS Network
Journal of neurodevelopmental disorders | 2018

Language delay is extremely common in children with autism spectrum disorder (ASD), yet it is unclear whether measurable variation in early language is associated with genetic liability for ASD. Assessment of language development in unaffected siblings of children with ASD can inform whether decreased early language ability aggregates with inherited risk for ASD and serves as an ASD endophenotype.

Pubmed ID: 30348077

Research resources used in this publication

None found

Antibodies used in this publication

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Associated grants

  • Agency: NICHD NIH HHS, United States
    Id: U54 HD083091
  • Agency: National Institute of Child Health and Human Development, International
    Id: P30HD062171
  • Agency: NICHD NIH HHS, United States
    Id: U54 HD087011
  • Agency: NICHD NIH HHS, United States
    Id: U54 HD079124
  • Agency: NIMH NIH HHS, United States
    Id: K99 MH108700
  • Agency: NICHD NIH HHS, United States
    Id: U54 HD086984
  • Agency: NIMH NIH HHS, United States
    Id: K08 MH112891
  • Agency: NIMH NIH HHS, United States
    Id: K01 MH103594
  • Agency: NICHD NIH HHS, United States
    Id: R01 HD055741

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PubMed (tool)

RRID:SCR_004846

Public bibliographic database that provides access to citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. PubMed citations and abstracts include fields of biomedicine and health, covering portions of life sciences, behavioral sciences, chemical sciences, and bioengineering. Provides access to additional relevant web sites and links to other NCBI molecular biology resources. Publishers of journals can submit their citations to NCBI and then provide access to full-text of articles at journal web sites using LinkOut.

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Institute of Bioinformatics and Systems Biology; Neuherberg; Germany (tool)

RRID:SCR_011307

Hosts the Munich Information Center for Protein Sequences (MIPS) and its main focus is the genome-oriented bioinformatics, in particular the systematic analysis of genome information including the development and application of bioinformatics methods in genome annotation, expression analysis and proteomics. MIPS supports and maintains a set of generic databases as well as the systematic comparative analysis of microbial, fungal, and plant genomes.

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