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Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target.

Juho Heliste | Anne Jokilammi | Ilkka Paatero | Deepankar Chakroborty | Christoffer Stark | Timo Savunen | Maria Laaksonen | Klaus Elenius
BMC cardiovascular disorders | 2018

Receptor tyrosine kinases (RTK) are potential targets for the treatment of ischemic heart disease. The human RTK family consists of 55 members, most of which have not yet been characterized for expression or activity in the ischemic heart.

Pubmed ID: 30342492

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UniProt (tool)

RRID:SCR_002380

Collection of data of protein sequence and functional information. Resource for protein sequence and annotation data. Consortium for preservation of the UniProt databases: UniProt Knowledgebase (UniProtKB), UniProt Reference Clusters (UniRef), and UniProt Archive (UniParc), UniProt Proteomes. Collaboration between European Bioinformatics Institute (EMBL-EBI), SIB Swiss Institute of Bioinformatics and Protein Information Resource. Swiss-Prot is a curated subset of UniProtKB.

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Promega (tool)

RRID:SCR_006724

An Antibody supplier

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EMBOSS (tool)

RRID:SCR_008493

Software analysis package for molecular biology community. Automatically copes with data in variety of formats and allows transparent retrieval of sequence data from web. Libraries are provided with package. Provides toolkit for creating bioinformatics applications or workflows. Provides set of sequence analysis programs. Provided programs cover areas such as sequence alignment, rapid database searching with sequence patterns, protein motif identification, nucleotide sequence pattern analysis, codon usage analysis for small genomes, rapid identification of sequence patterns in large scale sequence sets, and presentation tools for publication.

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HL-1 (tool)

RRID:CVCL_0303

Cell line HL-1 is a Transformed cell line with a species of origin Mus musculus (Mouse)

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