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In vivo and in vitro assessment of mirtazapine pharmacokinetics in cats with liver disease.

Rikki L Fitzpatrick | Jessica M Quimby | Kellyi K Benson | Dominique Ramirez | Liberty G Sieberg | Luke A Wittenburg | Daniel L Gustafson
Journal of veterinary internal medicine | 2018

Liver disease (LD) prolongs mirtazapine half-life in humans, but it is unknown if this occurs in cats with LD and healthy cats.

Pubmed ID: 30307637

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: P30 CA046934

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PRISM (tool)

RRID:SCR_005375

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5,2022.Tool that predicts interactions between transcription factors and their regulated genes from binding motifs. Understanding vertebrate development requires unraveling the cis-regulatory architecture of gene regulation. PRISM provides accurate genome-wide computational predictions of transcription factor binding sites for the human and mouse genomes, and integrates the predictions with GREAT to provide functional biological context. Together, accurate computational binding site prediction and GREAT produce for each transcription factor: 1. putative binding sites, 2. putative target genes, 3. putative biological roles of the transcription factor, and 4. putative cis-regulatory elements through which the factor regulates each target in each functional role.

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