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Use of bioreactors for culturing human retinal organoids improves photoreceptor yields.

Patrick Ovando-Roche | Emma L West | Matthew J Branch | Robert D Sampson | Milan Fernando | Peter Munro | Anastasios Georgiadis | Matteo Rizzi | Magdalena Kloc | Arifa Naeem | Joana Ribeiro | Alexander J Smith | Anai Gonzalez-Cordero | Robin R Ali
Stem cell research & therapy | 2018

The use of human pluripotent stem cell-derived retinal cells for cell therapy strategies and disease modelling relies on the ability to obtain healthy and organised retinal tissue in sufficient quantities. Generating such tissue is a lengthy process, often taking over 6 months of cell culture, and current approaches do not always generate large quantities of the major retinal cell types required.

Pubmed ID: 29895313

Research resources used in this publication

None found

Antibodies used in this publication

None found

Associated grants

  • Agency: Medical Research Council, United Kingdom
    Id: MR/J004553/1
  • Agency: Medical Research Council, United Kingdom
    Id: MR/M007871/1

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This is a list of tools and resources that we have found mentioned in this publication.


Advanced 3D Visualization and Volume Modeling (tool)

RRID:SCR_007353

Software tool for visualizing, manipulating, and understanding data from tomography, microscopy, MRI and other imaging processes.Used to import and export options, to processes 3D image filtering and DTI based fiber tracking to visualization, volume and surface rendering, author tools for virtual reality navigation, video generation, and more.

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FlowJo (tool)

RRID:SCR_008520

Software for single-cell flow cytometry analysis. Its functions include management, display, manipulation, analysis and publication of the data stream produced by flow and mass cytometers.

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Miltenyi Biotec (tool)

RRID:SCR_008984

An Organization portal, Antibody supplier, Service resource,

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