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N-Acetylcysteine Reduces ROS-Mediated Oxidative DNA Damage and PI3K/Akt Pathway Activation Induced by Helicobacter pylori Infection.

Chuan Xie | Jian Yi | Jing Lu | Muwen Nie | Meifang Huang | Jianfang Rong | Zhenhua Zhu | Jiang Chen | Xiaoliang Zhou | Bimin Li | Haiming Chen | Nonghua Lu | Xu Shu
Oxidative medicine and cellular longevity | 2018

H. pylori infection induces reactive oxygen species- (ROS-) related DNA damage and activates the PI3K/Akt pathway in gastric epithelial cells. N-Acetylcysteine (NAC) is known as an inhibitor of ROS; the role of NAC in H. pylori-related diseases is unclear.

Pubmed ID: 29854076

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