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Publication

Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer.

Sonja Neumeyer | Barbara L Banbury | Volker Arndt | Sonja I Berndt | Stephane Bezieau | Stephanie A Bien | Dan D Buchanan | Katja Butterbach | Bette J Caan | Peter T Campbell | Graham Casey | Andrew T Chan | Stephen J Chanock | James Y Dai | Steven Gallinger | Edward L Giovannucci | Graham G Giles | William M Grady | Jochen Hampe | Michael Hoffmeister | John L Hopper | Li Hsu | Mark A Jenkins | Amit Joshi | Susanna C Larsson | Loic Le Marchand | Annika Lindblom | Victor Moreno | Mathieu Lemire | Li Li | Yi Lin | Kenneth Offit | Polly A Newcomb | Paul D Pharaoh | John D Potter | Lihong Qi | Gad Rennert | Clemens Schafmayer | Robert E Schoen | Martha L Slattery | Mingyang Song | Cornelia M Ulrich | Aung K Win | Emily White | Alicja Wolk | Michael O Woods | Anna H Wu | Stephen B Gruber | Hermann Brenner | Ulrike Peters | Jenny Chang-Claude
British journal of cancer | 2018

Substantial evidence supports an association between use of menopausal hormone therapy and decreased colorectal cancer (CRC) risk, indicating a role of exogenous sex hormones in CRC development. However, findings on endogenous oestrogen exposure and CRC are inconsistent.

Pubmed ID: 29795306

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Associated grants

  • Agency: NHGRI NIH HHS, United States
    Id: U01 HG004438
  • Agency: NHGRI NIH HHS, United States
    Id: U01 HG004446
  • Agency: NCI NIH HHS, United States
    Id: P01 CA087969
  • Agency: NHLBI NIH HHS, United States
    Id: HHSN268201100046C
  • Agency: NCI NIH HHS, United States
    Id: P30 CA076292
  • Agency: NCI NIH HHS, United States
    Id: U24 CA074799
  • Agency: WHI NIH HHS, United States
    Id: HHSN268201100004C
  • Agency: NCI NIH HHS, United States
    Id: U19 CA148107
  • Agency: NCI NIH HHS, United States
    Id: R01 CA059045
  • Agency: NHLBI NIH HHS, United States
    Id: HHSN268201100001I
  • Agency: NCI NIH HHS, United States
    Id: R01 CA197350
  • Agency: NCI NIH HHS, United States
    Id: R01 CA076366
  • Agency: NCI NIH HHS, United States
    Id: R35 CA197735
  • Agency: NCI NIH HHS, United States
    Id: U01 CA074799
  • Agency: NHLBI NIH HHS, United States
    Id: HHSN268201600002C
  • Agency: NCI NIH HHS, United States
    Id: P30 CA015704
  • Agency: NHLBI NIH HHS, United States
    Id: HHSN268201600018C
  • Agency: NHLBI NIH HHS, United States
    Id: HHSN268201100004I
  • Agency: NIDDK NIH HHS, United States
    Id: K01 DK110267
  • Agency: NCI NIH HHS, United States
    Id: K05 CA154337
  • Agency: NCI NIH HHS, United States
    Id: U24 CA074783
  • Agency: NCI NIH HHS, United States
    Id: R01 CA151993
  • Agency: NCI NIH HHS, United States
    Id: R01 CA189184
  • Agency: NCI NIH HHS, United States
    Id: R01 CA048998
  • Agency: NCI NIH HHS, United States
    Id: U01 CA137088
  • Agency: WHI NIH HHS, United States
    Id: HHSN268201100003C
  • Agency: Intramural NIH HHS, United States
    Id: Z01 CP010200
  • Agency: NCI NIH HHS, United States
    Id: U24 CA074794
  • Agency: NCI NIH HHS, United States
    Id: U24 CA074806
  • Agency: NCI NIH HHS, United States
    Id: U01 CA206110
  • Agency: NCI NIH HHS, United States
    Id: R01 CA137178
  • Agency: NCI NIH HHS, United States
    Id: U24 CA097735
  • Agency: NCI NIH HHS, United States
    Id: U01 CA074794
  • Agency: NCI NIH HHS, United States
    Id: P30 CA008748
  • Agency: NCI NIH HHS, United States
    Id: U01 CA167551
  • Agency: NCI NIH HHS, United States
    Id: R01 CA081488
  • Agency: NCI NIH HHS, United States
    Id: P30 CA014089
  • Agency: NCI NIH HHS, United States
    Id: R01 CA189532
  • Agency: NCI NIH HHS, United States
    Id: R01 CA143237
  • Agency: NHLBI NIH HHS, United States
    Id: HHSN268201600003C
  • Agency: NIA NIH HHS, United States
    Id: HHSN271201100004C
  • Agency: NCI NIH HHS, United States
    Id: R01 CA063464
  • Agency: NCI NIH HHS, United States
    Id: P01 CA033619
  • Agency: NCI NIH HHS, United States
    Id: UM1 CA186107
  • Agency: WHI NIH HHS, United States
    Id: HHSN268201100002C
  • Agency: NCI NIH HHS, United States
    Id: R01 CA207371
  • Agency: NHLBI NIH HHS, United States
    Id: HHSN268201600004C
  • Agency: NCI NIH HHS, United States
    Id: R01 CA060987
  • Agency: NCI NIH HHS, United States
    Id: U01 CA097735
  • Agency: NHLBI NIH HHS, United States
    Id: HHSN268201600001C
  • Agency: NCI NIH HHS, United States
    Id: UM1 CA167551
  • Agency: NCI NIH HHS, United States
    Id: U01 CA122839
  • Agency: NIH HHS, United States
    Id: S10 OD020069
  • Agency: NHLBI NIH HHS, United States
    Id: HHSN268201100003I
  • Agency: NHLBI NIH HHS, United States
    Id: HHSN268201100002I
  • Agency: NCI NIH HHS, United States
    Id: U01 CA074783
  • Agency: NCI NIH HHS, United States
    Id: U01 CA074806
  • Agency: NCI NIH HHS, United States
    Id: U24 CA074800
  • Agency: NCI NIH HHS, United States
    Id: P50 CA127003
  • Agency: NCI NIH HHS, United States
    Id: K07 CA190673
  • Agency: NCI NIH HHS, United States
    Id: U01 CA152756
  • Agency: NCI NIH HHS, United States
    Id: R37 CA054281
  • Agency: NCI NIH HHS, United States
    Id: U01 CA074800
  • Agency: WHI NIH HHS, United States
    Id: HHSN268201100001C

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NCBI database of Genotypes and Phenotypes (dbGap) (tool)

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Database developed to archive and distribute clinical data and results from studies that have investigated interaction of genotype and phenotype in humans. Database to archive and distribute results of studies including genome-wide association studies, medical sequencing, molecular diagnostic assays, and association between genotype and non-clinical traits.

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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