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Genomic evolution of Staphylococcus aureus isolates colonizing the nares and progressing to bacteremia.

Jeanne B Benoit | Daniel N Frank | Mary T Bessesen
PloS one | 2018

Nasal colonization by Staphylococcus aureus is a key risk factor for bacteremia. The objective of this study is to identify genomic modifications occurring in nasal carriage strains of S. aureus as they progress to bacteremia in a cohort of hospitalized patients.

Pubmed ID: 29723202

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This is a list of tools and resources that we have found mentioned in this publication.


Picard (tool)

RRID:SCR_006525

Java toolset for working with next generation sequencing data in the BAM format.

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FreeBayes (tool)

RRID:SCR_010761

A Bayesian genetic variant detector designed to find small polymorphisms, specifically SNPs, indels, MNPs, and complex events smaller than the length of a short-read sequencing alignment.

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FastTree (tool)

RRID:SCR_015501

Source code that infers approximately-maximum-likelihood phylogenetic trees from alignments of nucleotide or protein sequences. It uses the Jukes-Cantor or generalized time-reversible (GTR) models of nucleotide evolution and the JTT, WAG, or LG models of amino acid evolution.

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SnpSift (tool)

RRID:SCR_015624

Software toolkit for filtering and manipulating annotated files. After annotation, the software's filter function can find relevant genomic variants in large data files.

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