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Publication

Postprandial increase in serum CA125 as a surrogate biomarker for early diagnosis of ovarian cancer.

Zhuowei Gu | Yifeng He | Yue Zhang | Mo Chen | Keqi Song | Yuting Huang | Qing Li | Wen Di
Journal of translational medicine | 2018

CA125 is a prevalently used serum biomarker for detecting ovarian cancer over the last three decades. However, it has a significant deficiency in screening for early-stage cancer. With the purpose of exploring an effective approach to improve its performance in early diagnosis, we investigated the postprandial fluctuation pattern of cancer-derived CA125 and the underlying mechanism.

Pubmed ID: 29716620

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Associated grants

  • Agency: This work was supported by the National Key R&D Program of China, International
    Id: 2016YFC1303100
  • Agency: Science and Technology Commission of Shanghai Municipality, International
    Id: 15441905700
  • Agency: Science and Technology Commission of Shanghai Municipality, International
    Id: 15DZ1940502
  • Agency: Science and Technology Commission of Shanghai Municipality, International
    Id: 12411950200
  • Agency: Shanghai Municipal Commission of Health and Family Planning, International
    Id: 2013ZYJB0202
  • Agency: National Natural Science Foundation of China, International
    Id: 81572548
  • Agency: National Natural Science Foundation of China, International
    Id: 81772770
  • Agency: National Natural Science Foundation of China, International
    Id: 81272882

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New England Biolabs (tool)

RRID:SCR_013517

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OVCAR-3 (tool)

RRID:CVCL_0465

Cell line OVCAR-3 is a Cancer cell line with a species of origin Homo sapiens (Human)

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SK-OV-3 (tool)

RRID:CVCL_0532

Cell line SK-OV-3 is a Cancer cell line with a species of origin Homo sapiens (Human)

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BALB/cAnNCrl (tool)

RRID:MGI:2683685

laboratory mouse with name BALB/cAnNCrl from MGI.

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About

The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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