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Publication

A randomized trial to study the comparative efficacy of phenylbutyrate and benzoate on nitrogen excretion and ureagenesis in healthy volunteers.

Sandesh C S Nagamani | Umang Agarwal | Allison Tam | Mahshid Azamian | Ann McMeans | Inka C Didelija | Mahmoud A Mohammad | Juan C Marini
Genetics in medicine : official journal of the American College of Medical Genetics | 2018

Benzoate and phenylbutyrate are widely used in the treatment of urea cycle disorders, but detailed studies on pharmacokinetics and comparative efficacy on nitrogen excretion are lacking.

Pubmed ID: 29693650

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Associated grants

  • Agency: NICHD NIH HHS, United States
    Id: R03 HD078447
  • Agency: NIGMS NIH HHS, United States
    Id: T32 GM007526
  • Agency: NICHD NIH HHS, United States
    Id: U54 HD061221
  • Agency: NICHD NIH HHS, United States
    Id: U54 HD083092

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