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Reduction of Premature Aging Markers After Gastric Bypass Surgery in Morbidly Obese Patients.

P J Hohensinner | C Kaun | B Ebenbauer | M Hackl | S Demyanets | D Richter | M Prager | J Wojta | Gersina Rega-Kaun
Obesity surgery | 2018

Obesity is considered to be a major comorbidity. Obese patients suffer from an increased proinflammatory state associated with a premature aging phenotype including increased secretion of senescence-associated secretory proteins (SASP) and reduced telomere length. Micro-ribonucleic acids (miRNAs) are non-coding RNA molecules that could modify the post-transcriptional process. Several studies have reported associations between miRNAs and metabolic unhealthy conditions.

Pubmed ID: 29693219

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LightCycler Software (tool)

RRID:SCR_012155

Light cycler software for analysis of quatitative real time PCR

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