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Publication

Regeneration of Tracheal Tissue in Partial Defects Using Porcine Small Intestinal Submucosa.

Nelson Bergonse Neto | Lianna Ferrari Jorge | Julio C Francisco | Bruna Olandoski Erbano | Barbara Evelin Gonçalves Barboza | Larissa Luvison Gomes da Silva | Marcia Olandoski | Katherine Athayde Teixeira de Carvalho | Luiz Felipe Pinho Moreira | Jose Rocha Faria Neto | Eltyeb Abdelwahid | Luiz Cesar Guarita-Souza
Stem cells international | 2018

Surgical correction of tracheal defects is a complex procedure when the gold standard treatment with primary end-to-end anastomosis is not possible. An alternative treatment may be the use of porcine small intestinal submucosa (SIS). It has been used as graft material for bioengineering applications and to promote tissue regeneration. The aim of this study was to evaluate whether SIS grafts improved tracheal tissue regeneration in a rabbit model of experimental tracheostomy.

Pubmed ID: 29681948

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