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ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection.

Wen-Han Yu | Cormac Cosgrove | Christoph T Berger | Patrick C Cheney | Marina Krykbaeva | Arthur Y Kim | Lia Lewis-Ximenez | Georg M Lauer | Galit Alter
Pathogens & immunity | 2018

Hepatitis B virus (HBV) affects up to 400 million people worldwide and accounts for approximately one million deaths per year from liver pathologies. Current treatment regimens are effective in suppressing viremia but usually have to be taken indefinitely, warranting research into new therapeutic approaches. Acute HBV infection in adults almost universally results in resolution of viremia, with the exception of immunocompromised persons, suggesting that the immune response can functionally cure or even eradicate HBV infection.

Pubmed ID: 29541698

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Associated grants

  • Agency: NIAID NIH HHS, United States
    Id: U19 AI066345
  • Agency: NIAID NIH HHS, United States
    Id: U19 AI082630

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K-562 (tool)

RRID:CVCL_0004

Cell line K-562 is a Cancer cell line with a species of origin Homo sapiens (Human)

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