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Development and evaluation of novel tumor-targeting paclitaxel-loaded nano-carriers for ovarian cancer treatment: in vitro and in vivo.

Shu Yao | Li Li | Xuan-Tao Su | Kai Wang | Zai-Jun Lu | Cun-Zhong Yuan | Jin-Bo Feng | Shi Yan | Bei-Hua Kong | Kun Song
Journal of experimental & clinical cancer research : CR | 2018

Ovarian cancer is the most leading cause of death and the third most common gynecologic malignancy in women. Traditional chemotherapy has inevitable drawbacks of nonspecific tumor targeting, high toxicity, and poor therapeutic efficiency. In order to overcome such shortcomings, we prepared a novel nano-carrier drug-delivery system to enhance the anti-tumor efficiency.

Pubmed ID: 29478415

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