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miR-155-5p modulates malignant behaviors of hepatocellular carcinoma by directly targeting CTHRC1 and indirectly regulating GSK-3β-involved Wnt/β-catenin signaling.

Gang Chen | Dongdong Wang | Xiongqi Zhao | Jun Cao | Yingpeng Zhao | Fan Wang | Jianhua Bai | Ding Luo | Li Li
Cancer cell international | 2017

Hepatocellular carcinoma (HCC) remains one of the most lethal cancers. MicroRNA-155 (miR-155) and collagen triple helix repeat containing 1 (CTHRC1) were found to be involved in hepatocarcinogenesis, but their detailed functions in HCC are unclear. Here, we aimed to investigate the underlying role of miR-155-5p and CTHRC1 in HCC.

Pubmed ID: 29234238

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HCCLM3 (tool)

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