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RAC3 influences the chemoresistance of colon cancer cells through autophagy and apoptosis inhibition.

María Fernanda Rubio | María Cecilia Lira | Francisco Damián Rosa | Adrían Dario Sambresqui | María Cecilia Salazar Güemes | Mónica Alejandra Costas
Cancer cell international | 2017

RAC3 coactivator overexpression has been implicated in tumorigenesis, contributing to inhibition of apoptosis and autophagy. Both mechanisms are involved in resistance to treatment with chemotherapeutic agents. The aim of this study was to investigate its role in chemoresistance of colorectal cancer.

Pubmed ID: 29209153

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HT-29 (tool)

RRID:CVCL_0320

Cell line HT-29 is a Cancer cell line with a species of origin Homo sapiens (Human)

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HCT 116 (tool)

RRID:CVCL_0291

Cell line HCT 116 is a Cancer cell line with a species of origin Homo sapiens (Human)

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LoVo (tool)

RRID:CVCL_0399

Cell line LoVo is a Cancer cell line with a species of origin Homo sapiens (Human)

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