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Effects of water, sanitation, handwashing, and nutritional interventions on telomere length among children in a cluster-randomized controlled trial in rural Bangladesh.

Audrie Lin | Benjamin F Arnold | Andrew N Mertens | Jue Lin | Jade Benjamin-Chung | Shahjahan Ali | Alan E Hubbard | Christine P Stewart | Abul K Shoab | Md Ziaur Rahman | Md Saheen Hossen | Palash Mutsuddi | Syeda L Famida | Salma Akther | Mahbubur Rahman | Leanne Unicomb | Firdaus S Dhabhar | Lia C H Fernald | John M Colford | Stephen P Luby
eLife | 2017

Shorter childhood telomere length (TL) and more rapid TL attrition are widely regarded as manifestations of stress. However, the potential effects of health interventions on child TL are unknown. We hypothesized that a water, sanitation, handwashing (WSH), and nutritional intervention would slow TL attrition during the first two years of life.

Pubmed ID: 28980942

Research resources used in this publication

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ATCC (tool)

RRID:SCR_001672

Global nonprofit biological resource center (BRC) and research organization that provides biological products, technical services and educational programs to private industry, government and academic organizations. Its mission is to acquire, authenticate, preserve, develop and distribute biological materials, information, technology, intellectual property and standards for the advancement and application of scientific knowledge. The primary purpose of ATCC is to use its resources and experience as a BRC to become the world leader in standard biological reference materials management, intellectual property resource management and translational research as applied to biomaterial development, standardization and certification. ATCC characterizes cell lines, bacteria, viruses, fungi and protozoa, as well as develops and evaluates assays and techniques for validating research resources and preserving and distributing biological materials to the public and private sector research communities.

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R Project for Statistical Computing (tool)

RRID:SCR_001905

Software environment and programming language for statistical computing and graphics. R is integrated suite of software facilities for data manipulation, calculation and graphical display. Can be extended via packages. Some packages are supplied with the R distribution and more are available through CRAN family.It compiles and runs on wide variety of UNIX platforms, Windows and MacOS.

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IMR-90 (tool)

RRID:CVCL_0347

Cell line IMR-90 is a Finite cell line with a species of origin Homo sapiens

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