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Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathway.

Yuehong Cui | Qian Li | Hong Li | Yan Wang | Hongshan Wang | Weidong Chen | Shangmin Zhang | Jian Cao | Tianshu Liu
OncoTargets and therapy | 2017

In recent years, understanding of the role of asparaginyl endopeptidase (AEP) in tumorigenesis has steadily increased. In this study, we investigated whether AEP expression correlates with sensitivity to chemotherapeutic drugs in gastric cancer and explored the mechanism.

Pubmed ID: 28223821

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