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Publication

Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.

Su Yao | Fangping Xu | Yu Chen | Yan Ge | Fen Zhang | Huijie Huang | Li Li | Danyi Lin | Xinlan Luo | Jie Xu | Donglan Luo | Xiaolan Zhu | Yanhui Liu
Journal of experimental & clinical cancer research : CR | 2017

The ubiquitin-ligase Fbw7 acts as a tumor suppressor, targeting lots of proto-oncogenes for proteolysis. However, the exact role of Fbw7 in diffuse large B-cell lymphoma (DLBCL) development remains unclear.

Pubmed ID: 28069035

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MP Biomedicals (tool)

RRID:SCR_013308

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HEK293T (tool)

RRID:CVCL_0063

Cell line HEK293T is a Transformed cell line with a species of origin Homo sapiens (Human)

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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