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Publication

Prenatal unhealthy diet, insulin-like growth factor 2 gene (IGF2) methylation, and attention deficit hyperactivity disorder symptoms in youth with early-onset conduct problems.

Jolien Rijlaarsdam | Charlotte A M Cecil | Esther Walton | Maurissa S C Mesirow | Caroline L Relton | Tom R Gaunt | Wendy McArdle | Edward D Barker
Journal of child psychology and psychiatry, and allied disciplines | 2017

Conduct problems (CP) and attention deficit hyperactivity disorder (ADHD) are often comorbid and have each been linked to 'unhealthy diet'. Early-life diet also associates with DNA methylation of the insulin-like growth factor 2 gene (IGF2), involved in fetal and neural development. We investigated the degree to which prenatal high-fat and -sugar diet might relate to ADHD symptoms via IGF2 DNA methylation for early-onset persistent (EOP) versus low CP youth.

Pubmed ID: 27535767

Research resources used in this publication

None found

Additional research tools detected in this publication

Antibodies used in this publication

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Associated grants

  • Agency: Medical Research Council, United Kingdom
    Id: MC_UU_12013/2
  • Agency: Medical Research Council, United Kingdom
    Id: MC_UU_12013/8
  • Agency: Wellcome Trust, United Kingdom
    Id: 102215
  • Agency: Medical Research Council, United Kingdom
    Id: MC_PC_15018
  • Agency: NICHD NIH HHS, United States
    Id: R01 HD068437
  • Agency: Biotechnology and Biological Sciences Research Council, United Kingdom
    Id: BBI025751/1
  • Agency: Medical Research Council, United Kingdom
    Id: G9815508
  • Agency: Wellcome Trust, United Kingdom
  • Agency: Biotechnology and Biological Sciences Research Council, United Kingdom
    Id: BB/I025263/1
  • Agency: Wellcome Trust, United Kingdom
    Id: 102215/2/13/2

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This is a list of tools and resources that we have found mentioned in this publication.

wateRmelon (tool)

RRID:SCR_001296

Software package for Illumina 450 methylation array normalization and metrics including 15 flavors of betas and three performance metrics, with methods for objects produced by methylumi, minfi and IMA packages.

View all literature mentions

GenomeStudio (tool)

RRID:SCR_010973

Visualize and analyze data generated by all of Illumina''s platforms.

View all literature mentions

ComBat (tool)

RRID:SCR_010974

Adjusting batch effects in microarray expression data using Empirical Bayes methods.

View all literature mentions

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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