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Rescue and evaluation of a recombinant PRRSV expressing porcine Interleukin-4.

Zhijun Li | Gang Wang | Yan Wang | Chong Zhang | Xinglong Wang | Baicheng Huang | Qiongyi Li | Liangliang Li | Biyun Xue | Peiyang Ding | Shahid Faraz Syed | Chengbao Wang | Xuehui Cai | En-Min Zhou
Virology journal | 2015

The current vaccines for porcine reproductive and respiratory syndrome virus (PRRSV) have failed to provide broad protection against infection by various strains of PRRSV. Porcine Interleukin-4 (pIL-4) plays an important role in the regulation of the immune response and has been used previously as an immunological adjuvant. The objective of this study was to construct a recombinant PRRSV expressing pIL-4 and to evaluate the immune response of the recombinant virus in piglets.

Pubmed ID: 26573719

Research resources used in this publication

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This is a list of tools and resources that we have found mentioned in this publication.


MARC-145 (tool)

RRID:CVCL_4540

Cell line MARC-145 is a Spontaneously immortalized cell line with a species of origin Chlorocebus pygerythrus

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