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Age-Dependent Pleiotropy Between General Cognitive Function and Major Psychiatric Disorders.

W David Hill | Gail Davies | CHARGE Cognitive Working Group | David C Liewald | Andrew M McIntosh | Ian J Deary
Biological psychiatry | 2016

General cognitive function predicts psychiatric illness across the life course. This study examines the role of pleiotropy in explaining the link between cognitive function and psychiatric disorder.

Pubmed ID: 26476593

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Associated grants

  • Agency: Wellcome Trust, United Kingdom
    Id: 104036
  • Agency: Biotechnology and Biological Sciences Research Council, United Kingdom
    Id: BB/F019394/1
  • Agency: Medical Research Council, United Kingdom
    Id: G0700704
  • Agency: Medical Research Council, United Kingdom
    Id: MR/K026992/1

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Broad Institute (tool)

RRID:SCR_007073

Biomedical and genomic research center located in Cambridge, Massachusetts, United States. Nonprofit research organization under the name Broad Institute Inc., and is partners with Massachusetts Institute of Technology, Harvard University, and the five Harvard teaching hospitals. Dedicated to advance understanding of biology and treatment of human disease to improve human health.

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100, 000 Genomes Project (tool)

RRID:SCR_010502

The project will focus on patients with a rare disease and their families and patients with cancer. The first samples for sequencing are being taken from patients living in England with discussions taking place with Scotland, Wales and Northern Ireland about potential future involvement. Genomics England, a company wholly owned and funded by the Department of Health, was set up to deliver this flagship project which will sequence 100,000 whole genomes from NHS patients by 2017. Its four main aims are; to create an ethical and transparent programme based on consent; to bring benefit to patients and set up a genomic medicine service for the NHS; to enable new scientific discovery and medical insights; and to kick start the development of a UK genomics industry.

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