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The introduction of cisplatin has improved the long-term survival rate in osteosarcoma patients. However, some patients are intrinsically resistant to cisplatin. This study reported that the activation of Notch1 is positively correlated with cisplatin sensitivity, evidenced by both clinical and in vitro data.
Pubmed ID: 24894297
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Cell line MG-63 is a Cancer cell line with a species of origin Homo sapiens (Human)
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