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PCR for detection of oseltamivir resistance mutation in influenza A(H7N9) virus.

Wei Wang | Zhigang Song | Wencai Guan | Yi Liu | Xiaonan Zhang | Lei Xu | Jianhua Li | Zhenghong Yuan | Yunwen Hu
Emerging infectious diseases | 2014

Sensitive molecular techniques are needed for rapid detection of the R292K oseltamivir-resistant mutant of influenza A(H7/N9) virus strain to monitor its transmission and guide antiviral treatment. We developed a real-time reverse transcription PCR and single nucleotide polymorphism probes to differentiate this mutant strain in mixed virus populations in human specimens.

Pubmed ID: 24751348

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RRID:SCR_008505

The directing and coordinating authority responsible for public health within the United Nations system. The WHO Regional Office for Europe (WHO/Europe) is one of the six regional offices around the world. It serves the WHO European Region, which comprises 53 countries from the Atlantic to the Pacific oceans. WHO/Europe collaborates with a range of public health stakeholders in the Region and globally, to ensure that coordinated action is taken to develop and implement efficient health policies and to strengthen health systems. WHO/Europe is made up of public health, scientific, and technical experts.

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