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Publication

Exposure to perfluorooctane sulfonate in utero reduces testosterone production in rat fetal Leydig cells.

Binghai Zhao | Li Li | Jieting Liu | Hongzhi Li | Chunlei Zhang | Pengfei Han | Yufei Zhang | Xiaohuan Yuan | Ren Shan Ge | Yanhui Chu
PloS one | 2014

Perfluorooctane sulfonate (PFOS) is a synthetic material that has been widely used in industrial applications for decades. Exposure to PFOS has been associated with decreased adult testosterone level, and Leydig cell impairment during the time of adulthood. However, little is known about PFOS effects in utero on fetal Leydig cells (FLC).

Pubmed ID: 24454680

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Rattus norvegicus with name SD from RGD.

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