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The prognostic role of BRAF mutation in metastatic colorectal cancer receiving anti-EGFR monoclonal antibodies: a meta-analysis.

Zi-Xu Yuan | Xiao-Yan Wang | Qi-Yuan Qin | De-Feng Chen | Qing-Hua Zhong | Lei Wang | Jian-Ping Wang
PloS one | 2013

BRAF mutation has been investigated as a prognostic factor in metastatic colorectal cancer (mCRC) undergoing anti-EGFR monoclonal antibodies (moAbs), but current results are still inconclusive. The aim of this meta-analysis was to evaluate the relationship between BRAF mutation status and the prognosis of mCRC patients treated with moAbs.

Pubmed ID: 23776587

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