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A Wolbachia wMel transinfection in Aedes albopictus is not detrimental to host fitness and inhibits Chikungunya virus.

Marcus S C Blagrove | Camilo Arias-Goeta | Cristina Di Genua | Anna-Bella Failloux | Steven P Sinkins
PLoS neglected tropical diseases | 2013

Wolbachia inherited intracellular bacteria can manipulate the reproduction of their insect hosts through cytoplasmic incompatibility (CI), and certain strains have also been shown to inhibit the replication or dissemination of viruses. Wolbachia strains also vary in their relative fitness effects on their hosts and this is a particularly important consideration with respect to the potential of newly created transinfections for use in disease control.

Pubmed ID: 23556030

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Associated grants

  • Agency: Wellcome Trust, United Kingdom
  • Agency: Wellcome Trust, United Kingdom
    Id: 095121
  • Agency: Biotechnology and Biological Sciences Research Council, United Kingdom
    Id: BB/G016976/1

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Vero (tool)

RRID:CVCL_0059

Cell line Vero is a Spontaneously immortalized cell line with a species of origin Chlorocebus sabaeus

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