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Publication

Doxorubicin influences the expression of glucosylceramide synthase in invasive ductal breast cancer.

Xiaofang Zhang | Xiaojuan Wu | Peng Su | Yongsheng Gao | Bin Meng | Yanlin Sun | Li Li | Zhiqiang Zhou | Gengyin Zhou
PloS one | 2012

Glucosylceramide synthase (GCS) is one enzyme that provides a major route for ceramide clearance. Recent evidence has indicated an important role for GCS in multidrug resistance (MDR) tumors. Doxorubicin (DOX)can modulate the expression of GCS in leukemia and ovary cell lines. However, few studies have investigated their relationship in breast cancer;

Pubmed ID: 23133636

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MCF-7 (tool)

RRID:CVCL_0031

Cell line MCF-7 is a Cancer cell line with a species of origin Homo sapiens (Human)

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MDA-MB-231 (tool)

RRID:CVCL_0062

Cell line MDA-MB-231 is a Cancer cell line with a species of origin Homo sapiens (Human)

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