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Publication

Inhibition of endothelial cell Ca²⁺ entry and transient receptor potential channels by Sigma-1 receptor ligands.

Mohamed S Amer | Lynn McKeown | Sarka Tumova | Ruifeng Liu | Victoria A L Seymour | Lesley A Wilson | Jacqueline Naylor | Katriona Greenhalgh | Bing Hou | Yasser Majeed | Paul Turner | Alicia Sedo | David J O'Regan | Jing Li | Robin S Bon | Karen E Porter | David J Beech
British journal of pharmacology | 2013

The Sigma-1 receptor (Sig1R) impacts on calcium ion signalling and has a plethora of ligands. This study investigated Sig1R and its ligands in relation to endogenous calcium events of endothelial cells and transient receptor potential (TRP) channels.

Pubmed ID: 23121507

Research resources used in this publication

None found

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Associated grants

  • Agency: Medical Research Council, United Kingdom
    Id: G1002076
  • Agency: British Heart Foundation, United Kingdom
  • Agency: Biotechnology and Biological Sciences Research Council, United Kingdom
  • Agency: Medical Research Council, United Kingdom
    Id: G0901761
  • Agency: Wellcome Trust, United Kingdom

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HEK293 (tool)

RRID:CVCL_0045

Cell line HEK293 is a Transformed cell line with a species of origin Homo sapiens (Human)

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HEK293 (tool)

RRID:CVCL_0045

Cell line HEK293 is a Transformed cell line with a species of origin Homo sapiens (Human)

View all literature mentions

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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