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Analysis of hypoxia and hypoxia-like states through metabolite profiling.

Julie E Gleason | David J Corrigan | James E Cox | Amit R Reddi | Lauren A McGinnis | Valeria C Culotta
PloS one | 2011

In diverse organisms, adaptation to low oxygen (hypoxia) is mediated through complex gene expression changes that can, in part, be mimicked by exposure to metals such as cobalt. Although much is known about the transcriptional response to hypoxia and cobalt, little is known about the all-important cell metabolism effects that trigger these responses.

Pubmed ID: 21931840

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: P30 DK072437
  • Agency: NCI NIH HHS, United States
    Id: T32 CA009110
  • Agency: NIGMS NIH HHS, United States
    Id: F32 GM093550
  • Agency: NIEHS NIH HHS, United States
    Id: R01 ES08996
  • Agency: NIEHS NIH HHS, United States
    Id: R01 ES008996
  • Agency: NIEHS NIH HHS, United States
    Id: P30 ES003819
  • Agency: NIEHS NIH HHS, United States
    Id: T32 ES007141
  • Agency: NIEHS NIH HHS, United States
    Id: T32 ES07141

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MassLynx (tool)

RRID:SCR_014271

Software which can acquire, analyze, manage, and share mass spectrometry data. MassLynx controls any Waters mass spectrometry system, from sample and solvent management components to mass spectrometer and auxiliary detectors. The software can acquire nominal mass, exact mass, MS/MS and exact mass MS/MS data. The software system also maintains and consolidates all user sample data. Optional Application Manager programs provide additional information for specific MS analyses and data.

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