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Peptide IC-20, encoded by skin kininogen-1 of the European yellow-bellied toad, Bombina variegata, antagonizes bradykinin-induced arterial smooth muscle relaxation.

Mu Yang | Mei Zhou | Bing Bai | Chengbang Ma | Le Wei | Lei Wang | Tianbao Chen | Chris Shaw
Journal of pharmacy & bioallied sciences | 2011

The objectives were to determine if the skin secretion of the European yellow-bellied toad (Bombina variegata), in common with other related species, contains a bradykinin inhibitor peptide and to isolate and structurally characterize this peptide.

Pubmed ID: 21687349

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WI (tool)

RRID:RGD_13508588

Rattus norvegicus with name WI from RGD.

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