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Publication

Protein kinase C inhibition ameliorates functional endothelial insulin resistance and vascular smooth muscle cell hypersensitivity to insulin in diabetic hypertensive rats.

Xiao Lu | James S Bean | Ghassan S Kassab | Mark D Rekhter
Cardiovascular diabetology | 2011

Insulin resistance, diabetes, and hypertension are considered elements of metabolic syndrome which is associated with vascular dysfunction. We investigated whether inhibition of protein kinase C (PKC) would affect vascular function in diabetic hypertensive (DH) rats.

Pubmed ID: 21635764

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Associated grants

  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL-084529

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RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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