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Publication

Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics.

Juan David Guzman | Abraham Wube | Dimitrios Evangelopoulos | Antima Gupta | Antje Hüfner | Chandrakala Basavannacharya | Md Mukhleshur Rahman | Christina Thomaschitz | Rudolf Bauer | Timothy Daniel McHugh | Irene Nobeli | Jose M Prieto | Simon Gibbons | Franz Bucar | Sanjib Bhakta
The Journal of antimicrobial chemotherapy | 2011

The aim of this study was to comprehensively evaluate the antibacterial activity and MurE inhibition of a set of N-methyl-2-alkenyl-4-quinolones found to inhibit the growth of fast-growing mycobacteria.

Pubmed ID: 21622974

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Antibodies used in this publication

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Associated grants

  • Agency: Austrian Science Fund FWF, Austria
    Id: P 21152
  • Agency: Medical Research Council, United Kingdom
    Id: G0801956

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Worldwide Protein Data Bank (wwPDB) (tool)

RRID:SCR_006555

Public global Protein Data Bank archive of macromolecular structural data overseen by organizations that act as deposition, data processing and distribution centers for PDB data. Members are: RCSB PDB (USA), PDBe (Europe) and PDBj (Japan), and BMRB (USA). This site provides information about services provided by individual member organizations and about projects undertaken by wwPDB. Data available via websites of its member organizations.

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RAW 264.7 (tool)

RRID:CVCL_0493

Cell line RAW 264.7 is a Cancer cell line with a species of origin Mus musculus

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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