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Polymorphisms of HIV-2 integrase and selection of resistance to raltegravir.

Danielle Perez Bercoff | Perrine Triqueneaux | Christine Lambert | Aboubacar Alassane Oumar | Anne-Marie Ternes | Sounkalo Dao | Patrick Goubau | Jean-Claude Schmit | Jean Ruelle
Retrovirology | 2010

Human Immunodeficiency Virus type 2 is naturally resistant to some antiretroviral drugs, restricting therapeutic options for patients infected with HIV-2. Regimens including integrase inhibitors (INI) seem to be effective, but little data on HIV-2 integrase (IN) polymorphisms and resistance pathways are available.

Pubmed ID: 21114823

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This is a list of tools and resources that we have found mentioned in this publication.


HIV Resistance Mutation Database (tool)

RRID:SCR_002904

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 4,2023.The HIV Resistance Mutation Database is a resource that allows users to download HIV sequences and information on HIV drug resistance and mutations. Users must download the data from either of two files available on the site, as the online portion of the database is no longer available. The system requires Mac OS9 to work. The DATABASES folder contains the current versions of 2 databases copied from resdb: BestDefined, and resistrelated. The BestDefined database is a list of the Brander epitopes. The resistrelated database is a compilation of HIV drug resistance mutations. The Bib and biblio files are the associated references for these databases. The RESIST_HTML folder contains the html files used by the resistance database web site.

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MT-4 (tool)

RRID:CVCL_2632

Cell line MT-4 is a Transformed cell line with a species of origin Homo sapiens

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