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Oncogenic role of the chromobox protein CBX7 in gastric cancer.

Xiao-Wei Zhang | Li Zhang | Wei Qin | Xiao-Hong Yao | Lei-Zhen Zheng | Xin Liu | Jin Li | Wei-Jian Guo
Journal of experimental & clinical cancer research : CR | 2010

Chromobox 7 (CBX7) is a Polycomb family protein that extends the lifespan of normal human cells via downregulating the expression of INK4a/ARF tumor suppressor locus. It was found that CBX7 expression was upregulated in lymphoma, but downregulated in some other human malignancies. The role of CBX7 in most types of cancer is still not clear. The purpose of this study is to investigate the role of CBX7 in gastric cancer.

Pubmed ID: 20723236

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NCI-N87 (tool)

RRID:CVCL_1603

Cell line NCI-N87 is a Cancer cell line with a species of origin Homo sapiens (Human)

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