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A parallel framework for simultaneous EEG/fMRI analysis: methodology and simulation.

Xu Lei | Chuan Qiu | Peng Xu | Dezhong Yao
NeuroImage | 2010

Concurrent EEG/fMRI recordings represent multiple, simultaneously active, regionally overlapping neuronal mass responses. To address the problems caused by the overlapping nature of these responses, we propose a parallel framework for Spatial-Temporal EEG/fMRI Fusion (STEFF). This technique adopts Independent Component Analysis (ICA) to recover the time-course and spatial mapping components from EEG and fMRI separately. These components are then linked concurrently in the spatial and temporal domain using an Empirical Bayesian (EB) model. This approach enables information one modality to be utilized as priors for the other and hence improves the spatial (for EEG) or temporal (for fMRI) resolution of the other modality. Consequently, STEFF achieves flexible and sparse matching among EEG and fMRI components with common neuronal substrates. Simulations under realistic noise conditions indicated that STEFF is a feasible and physiologically reasonable hybrid approach for spatiotemporal mapping of cognitive processing in the human brain.

Pubmed ID: 20083208

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Group ICA of fMRI Toolbox (tool)

RRID:SCR_001953

A MATLAB toolbox which implements multiple algorithms for independent component analysis and blind source separation of group (and single subject) functional magnetic resonance imaging data. GIFT works on MATLAB 6.5 and higher. Many ICA algorithms were generously contributed by Dr. Andrzej Cichocki.

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EEGLAB (tool)

RRID:SCR_007292

Interactive Matlab toolbox for processing continuous and event-related EEG, MEG and other electrophysiological data incorporating independent component analysis (ICA), time/frequency analysis, artifact rejection, event-related statistics, and several useful modes of visualization of the averaged and single-trial data. First developed on Matlab 5.3 under Linux, EEGLAB runs on Matlab v5 and higher under Linux, Unix, Windows, and Mac OS X (Matlab 7+ recommended). EEGLAB provides an interactive graphic user interface (GUI) allowing users to flexibly and interactively process their high-density EEG and other dynamic brain data using independent component analysis (ICA) and/or time/frequency analysis (TFA), as well as standard averaging methods. EEGLAB also incorporates extensive tutorial and help windows, plus a command history function that eases users'' transition from GUI-based data exploration to building and running batch or custom data analysis scripts. EEGLAB offers a wealth of methods for visualizing and modeling event-related brain dynamics, both at the level of individual EEGLAB ''datasets'' and/or across a collection of datasets brought together in an EEGLAB ''studyset.'' For experienced Matlab users, EEGLAB offers a structured programming environment for storing, accessing, measuring, manipulating and visualizing event-related EEG data. For creative research programmers and methods developers, EEGLAB offers an extensible, open-source platform through which they can share new methods with the world research community by publishing EEGLAB ''plug-in'' functions that appear automatically in the EEGLAB menu of users who download them. For example, novel EEGLAB plug-ins might be built and released to ''pick peaks'' in ERP or time/frequency results, or to perform specialized import/export, data visualization, or inverse source modeling of EEG, MEG, and/or ECOG data. EEGLAB Features * Graphic user interface * Multiformat data importing * High-density data scrolling * Defined EEG data structure * Open source plug-in facility * Interactive plotting functions * Semi-automated artifact removal * ICA & time/frequency transforms * Many advanced plug-in toolboxes * Event & channel location handling * Forward/inverse head/source modeling

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