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Publication

Hypoxic "second hit" in leukocytes from trauma patients: Modulation of the immune response by histone deacetylase inhibition.

Elizabeth A Sailhamer | Yongqing Li | Eleanor J Smith | Baoling Liu | Fahad Shuja | Chad P Soupir | Marc A DeMoya | George C Velmahos | Hasan B Alam
Cytokine | 2010

Histone deacetylase inhibitors (HDACI), can improve survival after lethal hemorrhagic shock, and modulate the inflammatory response after hemorrhage/lipopolysaccharide (LPS). The current experiments were designed to study the effects of HDACI after hemorrhage and severe hypoxia.

Pubmed ID: 20056553

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Associated grants

  • Agency: NIGMS NIH HHS, United States
    Id: F32 GM79880

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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