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N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels.

Bernhard Aigner | Birgit Rathkolb | Martina Klempt | Sibylle Wagner | Dian Michel | Martin Hrabé de Angelis | Eckhard Wolf
Journal of biomedical science | 2009

Clinical chemical blood analysis including plasma electrolytes is routinely carried out for the diagnosis of various organ diseases. Phenotype-driven N-ethyl-N-nitrosourea (ENU) mouse mutagenesis projects used plasma electrolytes as parameters for the generation of novel animal models for human diseases.

Pubmed ID: 19505327

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