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Acute phase protein response in an experimental model of ovine caseous lymphadenitis.

Peter D Eckersall | Fraser P Lawson | Laura Bence | Mary M Waterston | Tamara L Lang | William Donachie | Michael C Fontaine
BMC veterinary research | 2007

Caseous lymphadenitis (CLA) is a disease of small ruminants caused by Corynebacterium pseudotuberculosis. The pathogenesis of CLA is a slow process, and produces a chronic rather than an acute disease state. Acute phase proteins (APP) such as haptoglobin (Hp) serum amyloid A (SAA) and alpha1 acid glycoprotein (AGP) are produced by the liver and released into the circulation in response to pro-inflammatory cytokines. The concentration of Hp in serum increases in experimental CLA but it is not known if SAA and AGP respond in parallel or have differing response profiles.

Pubmed ID: 18093286

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Minitab (tool)

RRID:SCR_014483

A statistical software package that allows the user to import data, create graphs, and perform statistical analysis. It can perform basic statistical tests like descriptive statistics, hypothesis tests, confidence intervals, and normality tests as well as regression and ANOVA and quality assessment.

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