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Posttraumatic secondary brain insults exacerbates neuronal injury by altering metabotropic glutamate receptors.

Zhou Fei | Xiang Zhang | Hong-Min Bai | Xiao-Fan Jiang | Xia Li | Wei Zhang | Wei Hu
BMC neuroscience | 2007

Our previous studies indicated that metabotropic glutamate receptors (mGluRs) are deeply involved in the secondary processes after diffuse brain injury (DBI). In the present study, we used a rodent DBI model to determine whether hypotension exacerbates neuronal injury as a secondary brain insult (SBI) after traumatic brain injury (TBI) by changing the expression of metabotropic glutamate receptors (mGluRs) in the cerebral cortex.

Pubmed ID: 18021417

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Washington University Basic Local Alignment Search Tool (tool)

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It is used to compare a novel sequence with those contained in nucleotide and protein databases by aligning the novel sequence with previously characterized genes.

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