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Nanosize titanium dioxide stimulates reactive oxygen species in brain microglia and damages neurons in vitro.

Thomas C Long | Julianne Tajuba | Preethi Sama | Navid Saleh | Carol Swartz | Joel Parker | Susan Hester | Gregory V Lowry | Bellina Veronesi
Environmental health perspectives | 2007

Titanium dioxide is a widely used nanomaterial whose photo-reactivity suggests that it could damage biological targets (e.g., brain) through oxidative stress (OS).

Pubmed ID: 18007996

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Ingenuity Pathways Knowledge Base (tool)

RRID:SCR_008117

A horizontally and vertically structured database that pulls scientific and medical information and describes it consistently using the Ingenuity Ontology. The Knowledge Base pulls information from journals, public molecular content databases, and textbooks. Data is curated and and integrated into the Knowledge Base .

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Ingenuity Pathway Analysis (tool)

RRID:SCR_008653

A web-based software application that enables users to analyze, integrate, and understand data derived from gene expression, microRNA, and SNP microarrays, metabolomics, proteomics, and RNA-Seq experiments, and small-scale experiments that generate gene and chemical lists. Users can search for targeted information on genes, proteins, chemicals, and drugs, and build interactive models of experimental systems. IPA allows exploration of molecular, chemical, gene, protein and miRNA interactions, creation of custom molecular pathways, and the ability to view and modify metabolic, signaling, and toxicological canonical pathways. In addition to the networks and pathways that can be created, IPA can provide multiple layering of additional information, such as drugs, disease genes, expression data, cellular functions and processes, or a researchers own genes or chemicals of interest.

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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