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Previous studies have shown that common human coronavirus might be neurotropic, although it was first isolated as a pathogen of the respiratory tract. We noticed that a few patients with severe acute respiratory syndrome (SARS) experienced central nervous symptoms during the course of illness. In the present study, we isolated a SARS coronavirus strain from a brain tissue specimen obtained from a patient with SARS with significant central nervous symptoms.
Pubmed ID: 16163626
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Cell line Vero C1008 is a Spontaneously immortalized cell line with a species of origin Chlorocebus sabaeus
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