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Total 2403 Results
| Label | Description | ILX | Version | Created CID | Modified Time | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| low-threshold mechanoreceptor (LTMR) neuron | The mammalian cutaneous low-threshold mechanoreceptors (LTMRs) are a diverse set of primary somatosensory neurons that function to sense external mechanical force. Generally, LTMRs are composed of Aβ-LTMRs, Aδ-LTMRs, and C-LTMRs, which have distinct molecular, physiological, anatomical, and functional features. https://doi.org/10.1002/wdev.229 | ILX:0796519 | 1 | SPARC SAWG | 07/11/2025 | SPARC SAWG | term | 07/11/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| high-threshold mechanoreceptor (HTMR) neuron | High-threshold mechanoreceptors (HTMRs) are a broad category of mechanonociceptive sensory neurons that are optimally excited by noxious mechanical stimuli. HTMRs include Aδ and C free nerve endings that innervate the epidermis both in glabrous and hairy skin. https://doi.org/10.1016/j.neuron.2013.07.051 | ILX:0796520 | 1 | SPARC SAWG | 07/11/2025 | SPARC SAWG | term | 07/11/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| proprioceptive neuron | Proprioception is the sense of self-movement, force, and body position. Proprioception is mediated by proprioceptors, a type of sensory receptor, located within muscles, tendons, and joints.https://en.wikipedia.org/wiki/Proprioception | ILX:0796521 | 2 | SPARC SAWG | 07/11/2025 | SPARC SAWG | term | 07/11/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| field receptor sensory neuron | Field receptor neurons (Aβ Field‑LTMRs) are a subtype of large-diameter, fast-conducting Aβ low-threshold mechanoreceptors that innervate hairy skin via circumferential (field-type) endings, exhibiting weak but spatially distributed mechanosensitivity and responding to gentle stroking over broad receptive fields. https://doi.org/10.1038/s41583-021-00489-x | ILX:0796522 | 1 | SPARC SAWG | 07/11/2025 | SPARC SAWG | term | 07/11/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| heat-sensitive sensory neuron | A heat-sensitive sensory neuron is a type of peripheral sensory neuron that responds to increases in temperature and expresses thermosensitive ion channels such as TRPV1, mediating the detection of noxious or innocuous heat stimuli. https://en.wikipedia.org/wiki/TRPV1 | ILX:0796523 | 1 | SPARC SAWG | 07/11/2025 | SPARC SAWG | term | 07/11/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| cold-sensitive sensory neuron | A cold-sensitive sensory neuron is a peripheral sensory neuron that responds to decreases in temperature, often expressing the ion channel TRPM8, and contributes to the perception of cool or noxious cold stimuli. https://en.wikipedia.org/wiki/TRPM8 | ILX:0796524 | 1 | SPARC SAWG | 07/11/2025 | SPARC SAWG | term | 07/11/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| low-threshold mechanosensitivity (LTM) phenotype | A functional phenotype in which a sensory neuron or receptor responds to light mechanical stimuli, such as touch, hair deflection, or skin stretch. | ILX:0796525 | 1 | SPARC SAWG | 07/12/2025 | SPARC SAWG | term | 07/12/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| high-threshold mechanosensitivity (HTM) phenotype | A functional phenotype in which a sensory neuron or receptor responds only to intense or potentially damaging mechanical stimuli, such as pinch or high-pressure touch. | ILX:0796526 | 1 | SPARC SAWG | 07/12/2025 | SPARC SAWG | term | 07/12/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| field-type cutaneous mechanosensitivity phenotype | Response to gentle mechanical stimuli over large receptive fields, typically via circumferential or field endings. | ILX:0796527 | 1 | SPARC SAWG | 07/12/2025 | SPARC SAWG | term | 07/12/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| heat-sensitive phenotype | Response to noxious thermal stimuli. | ILX:0796528 | 2 | SPARC SAWG | 03/16/2026 | SPARC SAWG | term | 07/12/2025 | 0 | Ilias Ziogas | Susan Tappan |
| cold-sensitive phenotype | Phenotype of responding to cold or cooling stimuli. | ILX:0796529 | 2 | SPARC SAWG | 03/16/2026 | SPARC SAWG | term | 07/12/2025 | 0 | Ilias Ziogas | Susan Tappan |
| nociceptive circuit | Nociception refers to the central nervous system (CNS) and peripheral nervous system (PNS) processing of noxious stimuli, such as tissue injury and temperature extremes, which activate nociceptors and their pathways. Pain is the subjective experience one feels as a result of the activation of these pathways. Nociceptive circuits refer to the circuits involved in this signal trandusction. https://www.ncbi.nlm.nih.gov/books/NBK470255/ | ILX:0796530 | 1 | SPARC SAWG | 07/12/2025 | SPARC SAWG | term | 07/12/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| proprioceptive phenotype | Capability to detect muscle stretch or joint position, often via muscle spindle or Golgi tendon organ input. | ILX:0796531 | 1 | SPARC SAWG | 07/12/2025 | SPARC SAWG | term | 07/12/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| proprioceptive circuit | The proprioceptive circuit refers to the neural pathways and structures that enable the sense of body position, movement, and force. This system relies on proprioceptors, specialized sensory neurons located in muscles, tendons, and joints, which detect changes in length, tension, and joint angles. These sensory neurons send signals to the central nervous system, allowing the brain to coordinate and control movement. https://doi.org/10.1002/dvdy.24611 | ILX:0796532 | 1 | SPARC SAWG | 07/12/2025 | SPARC SAWG | term | 07/12/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| thermosensory circuit | A neural pathway that detects and transmits information about temperature changes (heat and cold) from the periphery to the central nervous system. | ILX:0796533 | 1 | SPARC SAWG | 07/17/2025 | SPARC SAWG | term | 07/17/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| mechanosensory circuit | A neural pathway that conveys tactile information such as touch, pressure, stretch, and vibration from the skin or internal tissues to the brain. | ILX:0796534 | 1 | SPARC SAWG | 07/17/2025 | SPARC SAWG | term | 07/17/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| pruriceptive circuit | A neural pathway specialized for detecting and transmitting itch signals, often mediated by specific receptors and distinct from pain pathways. | ILX:0796535 | 1 | SPARC SAWG | 07/17/2025 | SPARC SAWG | term | 07/17/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| chemosensory circuit | A neural pathway that senses chemical stimuli—such as pH, inflammatory mediators, or metabolic byproducts—within the body or environment and relays this information to the nervous system. | ILX:0796536 | 1 | SPARC SAWG | 07/17/2025 | SPARC SAWG | term | 07/17/2025 | 0 | Ilias Ziogas | Ilias Ziogas |
| cardiac interganglionic nerve | A nerve that goes between the intrinsic cardiac ganglia (atrial and ventricular). | ILX:0796679 | 2 | SPARC SAWG | 08/28/2025 | SPARC SAWG | term | 08/19/2025 | 0 | Susan Tappan | Tom Gillespie |
| right C cardiovascular and pharyngeal branch of cervical vagus nerve | The third branch of the right cervical vagus nerve identified during dissection that targets cardiovascular and pharyngeal structures. This is a REVA annotation term, created specifically for annotation of vagus nerve images generated as part of the experimental project funded by SPARC. [unvetted] | ILX:0796682 | 1 | SPARC SAWG | 08/21/2025 | SPARC SAWG | term | 08/21/2025 | 0 | Susan Tappan | Susan Tappan |
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