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http://ki.se/en/meb/cancer-of-the-prostate-in-sweden-caps
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 3rd,2023. We have completed the recruitment of this population-based prostate cancer case-control study, one of the largest prostate cancer case-control study populations available so far. This study population was recruited in two phases. The inclusion and exclusion criteria were the same for the first (CAPS1) and second phase (CAPS2), except for the timeframe. In total, 3,030 cases and 1,960 controls participated in CAPS donating blood samples and answering a questionnaire during 2001-2003. In addition we have detailed clinical information on all 3,000 cases. With data generated from CAPS we have 25 published papers and 10 manuscripts since 2004. During 2006 we completed a record linkage to the Cause of Death Registry to determine the cause of death for all participants. We could conclude that 347 of the cases in CAPS had died of prostate cancer. The CAPS study has provided data to several new studies on markers on prostate cancer progression. Sample types: * EDTA whole blood * DNA Number of sample donors: 5015 (sample collection completed)
Proper citation: Cancer of the Prostate in Sweden (CAPS) (RRID:SCR_006033) Copy
http://ki.se/imm/cefalo-studien
Saliva taken from participants in a study investigating the association between environmental exposures and brain tumors in children aged 7-19 years and the interaction between these risk factors and genetic polymorphisms, which may confer susceptibility to effects of exogenous agents. Sample types: * Saliva Number of sample donors: 886 (sample collection completed)
Proper citation: KI Biobank - CEFALO (RRID:SCR_006034) Copy
https://scicrunch.org/scicrunch/data/source/nlx_154697-3/search?q=*
A virtual database currently indexing available cell lines from: Coriell Cell Repositories, International Mouse Strain Resource (IMSR), ATCC, NIH Human Pluripotent Stem Cell Registry, NIGMS Human Genetic Cell Repository, and Developmental Therapeutics Program.
Proper citation: Integrated Cell Lines (RRID:SCR_008994) Copy
Provides sterile biologic implants of human bone and tissues used in spine, sports medicine, orthopedic, dental and other specialty surgeries.
Proper citation: RTI Biologics (RRID:SCR_010721) Copy
Provides human tissue for drug discovery scientists. * Human Biospecimens: Frozen & Fixed Human Tissues; Human RNA/DNA; Human Primary Cells / Cell lines; Custom Procurement; Oncology tissue, biofluid and RNA sets at special prices * Human Tissue-Based Services: Gene Expression, Molecular Pathology, Biochemical Pharmacology, Metabolism and Toxicity * Predictive Human Disease Models
Proper citation: Asterand (RRID:SCR_010703) Copy
http://www.tissue-solutions.com/
Tissue Solutions offers you a single point to access the entire range of human biological materials for all your research and development needs. This includes diseased and normal tissues in fresh, frozen and FFPE formats. Using our large network of ethical sources we find the tissues you require, to your specifications and will deliver them to your door. Our goal is to provide high quality and well characterized samples to biotech companies, the pharmaceutical community and contract research organizations worldwide. We also organize customized and prospective tissue acquisition projects and give specialized advice relating to all aspects of the acquisition process, including intellectual input on project design. We appreciate that you would rather spend your time finding new biomarkers and developing, testing and validating novel drugs to cure human disease than spend your time sourcing material to help you do your work, so let our dedicated Tissue Acquisitionists lessen your workload and become a virtual part of your team.
Proper citation: Tissue Solutions (RRID:SCR_010672) Copy
http://mayovalidation.com/quality-biospecimens/
A core laboratory facility provides high-volume, high-quality tissue and biospecimen preparation and processing in support of Mayo research. Mayo Validation Support Services utilizes these resources to deliver extensive validation capabilities specific to individualized Sponsor requirements. Medical scientific expertise at Mayo Clinic allows for unique collaborations combining quality biospecimens linked to comprehensive clinical outcomes. Biospecimens can be accessed via archives or prospectively collected via individualized standard operating procedures. Patient information for all biospecimens is protected through oversight by an Institutional Review Board (IRB). Specimens may be collected and/or processed in a variety of customized formats for individual collaborations. Typical formats include: * Specimen Processing: Tissue RNA/DNA extraction capabilities, Paraffin and frozen sectioning, Immunostaining, Digital imaging, Laser capture microdissection, Tissue microarray construction, Preparation of protocol-collected tissue (FFPE, OCT, Snap-frozen, PBS) * Blood: Circulating tumor cells, Serum, Plasma, PBMC, Whole blood for FACS analysis, Blood smears * Other: Induced sputum, Saliva, Buccal swabs, Lip biopsies, Colonoscopy biopsies, Synovium, Stool, Urine Biospecimens located within archives are well-characterized and associated with phenotypic information. Multiple types and formats of biospecimens are available for customized validation purposes.
Proper citation: Mayo Validation Support Services Biobank (RRID:SCR_010745) Copy
Genetic Alliance Registry and BioBank is a centralized, clinical data registry and sample repository (including DNA, serum, cells and tissues) that enables translational research. It is a nonprofit organization established by seven patient advocacy organizations. These organizations share resources for their BioBanks, such as the contract to the independent lab that processes the samples, but each organization will maintain ownership, control and costs associated with their sample collection. Founded in 2003, this cooperative venture provides shared infrastructure and customized solutions for disease advocacy organizations to lead sophisticated research initiatives. Genetic Alliance Registry and BioBank is an advocacy owned repository for biological samples and clinical data. It provides: * Centralized, standardized collection and archiving * Highest biorepository and participant protection standards * Open access for all organization approved researchers * Advocacy organization control
Proper citation: Genetic Alliance Biobank (RRID:SCR_010625) Copy
http://www.scienceexchange.com/facilities/specimen-bank-bwh-harvard
Core facility that provides the following services: Open repositories service, Sample processing service, Medical/pathology informatics support service, BWH tissue repository service.
The Specimen Bank provides materials to investigators with IRB-approved protocols. Staff are available to assist with selection of samples appropriate for downstream applications, development of processing protocols or preparation of derivatives from clinical materials. IT Staff are also available to assist researchers with creation of queries for prospective sample collection or queries to select samples from specific cohorts. Their goal is to drive quality research in an efficient and cost-effective manner. Each year they provide tens of thousands of samples to area researchers. Getting started: Partners investigators and study staff may request a Crimson user account to help manage studies and collected materials.
Proper citation: BWH Specimen Bank (RRID:SCR_012316) Copy
Provides access to large scale cell culture at reasonable cost. The Cell Culture Center has experience with the production of over 1700 cell lines. Numerous common cell lines, such as HeLa, CHO, 293, BHK, and hybridomas are routinely produced at the Center. We will adapt your cell line or custom protocol to large scale production then deliver the cells in the quantity and frequency you need. Large Scale Production Services: Mammalian cells: Suspension culture (1 to 400 liters per day), Anchorage dependent culture (1 to 200 roller bottles per batch), Purified monoclonal antibodies (10 mg to 100 grams), Non-hybridoma cell secreted proteins, Conditioned media Secreted proteins from suspension cultures can be produced in automated hollow fiber bioreactor systems. These systems may be considered after initial static culture production yields are determined. Upon determining the quantities requested by the investigator, the appropriate automated system will be used. For more information on the automated instrumentation available for the use of secreted protein production, please refer to the Biovest International web page (www.biovest.com). Working with our experienced personnel and quality controlled, state-of-the-art facilities also permits access to large quantities of cells or protein so you aren''t limited by the cell culture capacities of your own laboratory. The Center fulfills the needs of small research laboratories as well as those of larger institutions. Customers from all sectors of the research and industrial community are welcome to inquire about our services. If you''d like to inquire about using our services, use the contact infromation below. Key words: Cell, cells, culture, monoclonal, antibodies, antibody.
Proper citation: National Cell Culture Center (RRID:SCR_013467) Copy
Biospecimen repository of normal and diseased human material from a variety of tissues and conditions along with clinical annotation. Both frozen aliquots and paraffin embedded tissue are available. Biospecimens are available to qualified researchers with IRB approval. * Preliminary inquires please contact Cheryl Spencer at cheryl.spencer (at) bmc.org
Proper citation: Boston University Biospecimen Archive Research Core (RRID:SCR_005363) Copy
http://med.brown.edu/neurology/brainbank/index.html
A tissue resource center which facilitates research into the relationship between Alzheimer's disease and other brain disorders such as strokes and mental illnesses. Most donations have been obtained from Alzheimer's patients. Normal controls are available, many of which are from subjects with close relatives with Alzheimer's. The Brown BTRC also supports a collection of brain tumor cases that were harvested from patients who underwent surgery and who were enrolled in a clinical trial for the development of new treatments for brain cancer.
Proper citation: Brown Brain Tissue Resource Center (RRID:SCR_005392) Copy
http://www.einstein.yu.edu/centers/ictr/
Patient-derived specimens are essential to research in genomics, proteomics, and biomarkers. We provide banking for biological fluid and tissue specimens as well as human DNA and RNA. We provide secure archival sample storage as well as clinically-annotated specimen biobanks for defined research projects. The core serves the human research blood and tissue banking needs of clinical and translational researchers. Samples can be banked by an individual PI or by a consortium of investigators. All samples are tracked and archived using a secure tracking database, the Einstein-Montefiore Bio-Repository Databank (EM-BRED), http://informatics30.aecom.yu.edu/em-bred/default.aspx. EM-BRED provides qualified investigators with a solution to securely link patient specimens to clinical and pathological data. It consists of a user-friendly query engine that allows for comprehensive specimen search, and ultimately to build clinical annotations of relevance. The facility works under the best practices set out by NCI and ISBER (2006) for collection, storage, and retrieval of human biological materials for research.
Proper citation: Einstein-Montefiore Institute for Clinical and Translational Research Biorepository (RRID:SCR_005297) Copy
http://www.wanprc.org/primate-resources/pathology-tissue-program/
A comparative pathology unit offering pathology support, training programs, and a Tissue Distribution Program (TDP). The TDP provides a wide variety of nonhuman primate tissues to investigative groups within and outside the Washington National Primate Research Center (WaNPRC). Tissue and pathology services (ACVP board certified Veterinary Pathologists), full histology services (including immunohistochemistry and frozen sectioning), and protocol development consultation are available. The Pathology and Tissue Program is an integration of comparative pathology activities occurring at the Washington National Primate Research Center and those occurring within the University of Washington Department of Comparative Medicine ((DCM). Using this model, Washington National Primate Research Center pathologists provide routine pathology support for Washington National Primate Research Center animals, with ancillary support, expertise, and guidance provided by DCM pathologists and mission-dedicated technicians and laboratories. This integrated comparative pathology unit also provides an excellent training opportunity for students such as those enrolled in the Department of Comparative Medicine post-doctoral training program, which offers training in laboratory animal medicine and comparative pathology. A particularly important function of this comparative pathology unit is support of the Tissue Distribution Program. The TDP provides a wide variety of nonhuman primate tissues to investigative groups within and outside the WaNPRC. This program is an extremely valuable method of conserving the nonhuman primate resource. NHP tissues and biological materials are collected in preparation for RNA/DNA isolation, cell culture, immunohistochemistry/histology, anatomic dissection, and cell sorting. Capabilities of the TDP include, but are not limited to flash frozen preservation, sterile preparation, perfusion, technical surgical dissections, and OCT embedding. In conjunction with the Histology and Imaging core of the University of Washington DCM, research capabilities post-collection include in situ hybridization, confocal and fluorescent microscopy, live cell imaging (DeltaVision), and whole slide scanning with image analysis (Visiopharm, Nikon Elements, and Image Pro). Centralized coordination of nonhuman primate tissue requests with animal availability allows support for a large number of biomedical programs with significantly decreased impact on the animal resource.
Proper citation: WaNPRC Pathology and Tissue Program (RRID:SCR_005589) Copy
https://www.facebase.org/node/252
THIS RESOURCE IS NO LONGER IN SERVICE,documented on January,18, 2022. FaceBase Biorepository is now collecting biological samples from people with cleft lip/palate and their family members. Information for Prospective Cases: Clefts of the lip and/or palate can be caused by a wide range of genetic, environmental and other factors. The FaceBase Biorepository will serve as a common source of both biological samples and information that can be made available to investigators trying to determine the underlying cause of these common birth defects. Genetic studies, in particular, will benefit from both family history information and having samples from affected individuals as well as their family members. DNA is the information containing molecules found in all the cells of our body and can be easily obtained from material such as blood or saliva samples. As part of the FaceBase Biorepository, we are requesting families to submit biological samples from specific family members as well as information from other family members that might be affected with either the same condition or a similar condition. The medical and family history information that is collected includes other relevant information such as exposure to possible environmental causes during pregnancy. The biorepository is managed by Nichole Nidey, a research study coordinator, and Jeff Murray, a pediatric clinical geneticist and researcher. They are available to speak with family members regarding questions they may have, including providing information about the biorepository and making arrangements for the collection of samples for those who wish to participate. All participation is voluntary. Your name or other personally identifiable information (name, address, etc) will be removed before information is placed in the biorepository. Summary data to show how the database itself has been used overall as well as updates on whether specific findings might have been made using this database will be available on the FaceBase website at www.facebase.org. A newsletter containing this information will also be given to families and referring clinicians so that they may discuss the specifics with the families if there appears to be information that might be relevant in a particular case. Families will also need to sign a consent form that has been approved by the Institutional Review Board at the University of Iowa. Also, any submitted samples or data can also be removed from the database at any time should the family no longer wish to participate. Investigators interested in requesting DNA samples or for more information, please contact cleftresearch (at) uiowa.edu, Nichole Nidey, nichole-nidey (at) uiowa.edu or (319) 353-4365, or Jeff Murray, jeff-murray (at) uiowa.edu.
Proper citation: FaceBase Biorepository (RRID:SCR_006001) Copy
http://ki.se/ki/jsp/polopoly.jsp?d=29332&a=31537&l=en
THIS RESOURCE IS NO LONGER IN SERVICE, documented on April 4, 2014. Tissue Biobank collects samples from different types of cancers patients prospectively. Blood samples are being sent to KI Biobank for DNA extraction and storage. Number of sample donors: 611 (June 2010)
Proper citation: KI Biobank - Tissue Biobank (RRID:SCR_006043) Copy
http://www.alphaone.ufl.edu/dna_tissue_bank1.html
The Alpha-1 Foundation DNA and Tissue Bank, established in 2000 by the Alpha-1 Foundation, is a repository specifically for medical information (hyperlink to data points) and tissue samples (DNA, plasma, lung/liver) for alpha-1-antitrypsin deficient individuals, their family and friends. The Bank serves the international scientific community. Currently the Bank has the largest collection of DNA in the world for Alpha-1-antitrypsin research studies. The Alpha-1 Foundation has established a Tissue Bank Advisory Committee which includes a wide representation of physicians, ethicists, attorneys, consumers as well as international experts in tissue banking. Collectively this Advisory Committee reviews requests for research. At this time the Bank has over 2400 members who have provided valuable medical and/or tissue samples. For investigators interested in obtaining tissue samples with phenotypes from the Bank, please contact the Alpha-1 Foundation or our research staff at the University of Florida.
Proper citation: University of Florida DNA and Tissue Bank (RRID:SCR_006581) Copy
SMBRR maintains the only self-sustaining national research resource of laboratory-born squirrel monkeys, their tissues and other biological materials, as well as the expertise to carry out research on this animal. Scientists with NIH grants utilize squirrel monkeys to study many diseases that threaten human health including Alzheimer's disease and other disorders of the central nervous system, drug addiction, malaria, and viral diseases. Center that carries out research on squirrel monkey biology and its research uses. It meets the needs of the biomedical research community in three ways: providing national resource for laboratory-born squirrel monkeys, having active research component that continues to add new information about the biology of the squirrel monkey with a particular emphasis on reproduction and colony management, and acts as a source of expertise for squirrel monkey biology, management and husbandry.
Proper citation: Squirrel Monkey Breeding and Research Resource (RRID:SCR_006291) Copy
Biobank Ireland Trust promotes the development of an Irish Hospital Biobank Network to coordinate collection of small samples of cancer and normal tissue and coded patient data from those having a cancer operation. This will facilitate international molecular research collaborations, which may help identify the best treatment for each individual patient - personalized medicine. Biobank Ireland is promoting the development of a Hospital Biobank Network throughout the island of Ireland as a bridge between cancer research and care. This new infrastructure will facilitate large national and international translational research collaborations that will raise Ireland''s research profile and benefit those with cancer. Researchers will have online access to samples and to restricted patient data from participating hospitals and an equitable withdrawal process for scientifically and ethically approved projects. Important research results will be explained to the public. Other Objectives: * To facilitate (inter)national translational research collaborations that may lead to new tests and better, less toxic treatments for those with cancer * To enable molecular research on cancer tissue from clinical trials patients identify the best treatment for each individual patient ������??personalized medicine������?? * Researchers will have online access to samples and restricted patient data from participating hospitals, and a fair release process for scientifically and ethically approved projects * Biobank Ireland recognizes the need to have harmonization in biobanking around the world * Important research results will be explained to the public * Biobank Ireland will seek to have the hospital-based Biobank Network funded by government as standard of care
Proper citation: Biobank Ireland Trust (RRID:SCR_006430) Copy
http://www.mc.vanderbilt.edu/root/vumc.php?site=chtn%20western%20division
The Cooperative Human Tissue Network- Western Division at Vanderbilt University Medical Center is one of six institutions throughout the country funded by the National Cancer Institutes to procure and distribute remnant human tissues to biomedical researchers throughout the United States and Canada. CHTN operates through a shared networking system which allows investigators greater access to available research specimens. CHTN offers a variety of preparation and preservation techniques to ensure investigators are receiving the quality specimens needed for research. Remnant tissues are obtained from surgical resections and autopsies and are procured to the specifications of the investigator.
Proper citation: Cooperative Human Tissue Network Western Division at Vanderbilt University Medical Center (RRID:SCR_006661) Copy
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