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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
LIMMA
 
Resource Report
Resource Website
10000+ mentions
LIMMA (RRID:SCR_010943) LIMMA software application, software resource, data analysis software, data processing software Software package for the analysis of gene expression microarray data, especially the use of linear models for analyzing designed experiments and the assessment of differential expression. analysis, gene, expression, microarray, data, linear, model, bio.tools is used by: Glimma
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: GEO2R
is related to: Bioconductor
Free, Available for download, Freely available biotools:limma, OMICS_00769 https://omictools.com/limma-tool, https://bio.tools/limma, https://sources.debian.org/src/r-bioc-limma/ SCR_010943 Linear Models for Microarray Data 2026-07-28 09:42:56 24583
ArrayAnalysis.org
 
Resource Report
Resource Website
50+ mentions
ArrayAnalysis.org (RRID:SCR_010932) ArrayAnalysis.org service resource, data analysis service, software resource, production service resource, analysis service resource Tools for microarray quality control and pre-processing. r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:23620278 Acknowledgement requested OMICS_00742, biotools:arrayanalysis.org https://bio.tools/arrayanalysis.org SCR_010932 ArrayAnalysis 2026-07-28 09:42:59 72
nsSNPAnalyzer
 
Resource Report
Resource Website
10+ mentions
nsSNPAnalyzer (RRID:SCR_010780) nsSNPAnalyzer software application, service resource, data analysis software, data analysis service, data processing software, software resource, production service resource, analysis service resource A tool to predict whether a nonsynonymous single nucleotide polymorphism (nsSNP) has a phenotypic effect. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tennessee Health Science Center; Tennessee; USA
OMICS_00156, biotools:nssnpanalyzer https://bio.tools/nssnpanalyzer SCR_010780 nsSNPAnalyzer: predicting disease-associated nonsynonymous single nucleotide polymorphisms 2026-07-28 09:42:58 46
icy
 
Resource Report
Resource Website
100+ mentions
icy (RRID:SCR_010587) ICY software application, service resource, source code, software resource, data processing software, image processing software, software development environment, software development tool, software repository, image analysis software An open community platform for bioimage informatics providing the software resources to visualize, annotate and quantify bioimaging data. To bridge the gap between developers and users, it combines: a) an open-source image analysis software, offering a powerful and flexible environment for developers such as applied mathematicians to write algorithms fast and efficiently; b) a common set of tools to view and manipulate data, and a set of plugins to perform specific quantification or analysis on images; c) a community-based website centralizing all plugins and resources to facilitate their management and maximize their visibility towards users. Workspaces are virtual groups of plugins dedicated to a specific application or image processing domain. By downloading a workspace, ICY automatically installs all corresponding plugins. The workspaces are enabled, but the editing section is not ready yet. If you want to publish a plugin on this website, its code has to be GPL. Source code is available and provided in each application download. image analysis, microscopy, javascript, python, plugin, protocol, script, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Pasteur Institute
Centre National de la Recherche Scientifique ;
French National Research Agency ANR-10-INBS-04-06
PMID:22743774 Free, Open unspecified license, GNU General Public License, v3, The community can contribute to this resource biotools:icy, nlx_45928 https://bio.tools/icy SCR_010587 icy bioimage analysis 2026-07-28 09:42:52 320
Velvet
 
Resource Report
Resource Website
1000+ mentions
Velvet (RRID:SCR_010755) Velvet software application, data analysis software, sequence analysis software, software resource, data processing software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software package as de novo genomic assembler for short read sequencing technologies using de Bruijn graphs. Takes in short read sequences, removes errors, then produces high quality unique contigs, retrieves repeated areas between contigs. Can leverage very short reads in combination with read pairs to produce useful assemblies. Operating system Unix/Linux., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. de novo, genomic, assembly, short, read, sequencing, de Bruijn, graph, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Velvet-SC
is related to: shovill
has parent organization: European Bioinformatics Institute
EMBL PMID:18349386
DOI:10.1101/gr.074492.107
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00038, biotools:velvet https://www.ebi.ac.uk/~zerbino/velvet/, https://bio.tools/velvet, https://sources.debian.org/src/velvet/ SCR_010755 2026-07-28 09:42:56 1036
BWA
 
Resource Report
Resource Website
1000+ mentions
BWA (RRID:SCR_010910) BWA software application, data analysis software, sequence analysis software, software resource, data processing software, alignment software, image analysis software Software for aligning sequencing reads against large reference genome. Consists of three algorithms: BWA-backtrack, BWA-SW and BWA-MEM. First for sequence reads up to 100bp, and other two for longer sequences ranged from 70bp to 1Mbp. sequence, alignment, reference, genome, human, short, long, read, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: shovill
is related to: Proovread
is related to: BWA-MEM2
has parent organization: SourceForge
is required by: RelocaTE
PMID:19451168
PMID:20080505
DOI:10.1093/bioinformatics/btp324
Free, Available for download, Freely available SCR_015853, biotools:bwa-sw, OMICS_00654 https://sourceforge.net/projects/bio-bwa/files/, https://bio.tools/bwa-sw, https://sources.debian.org/src/bwa/ SCR_010910 Burrows-Wheeler Aligner (BWA), Burrows-Wheeler Aligner 2026-07-28 09:42:59 2291
KisSplice
 
Resource Report
Resource Website
10+ mentions
KisSplice (RRID:SCR_011893) KisSplice software application, software resource, data analysis software, data processing software Software tool that enables analysis of RNA-seq data with or without reference genome. Local transcriptome assembler for SNPs, indels and AS events. RNA-seq data analysis, with reference genome, without reference genome, local transcriptome assembler, SNPs, indels, AS events., bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.1186/1471-2105-13-S6-S5 Free, Available for download, Freely available biotools:KisSplice, OMICS_01321 https://bio.tools/KisSplice, https://sources.debian.org/src/kissplice/ SCR_011893 2026-07-28 09:42:57 20
ECHO
 
Resource Report
Resource Website
100+ mentions
ECHO (RRID:SCR_011851) ECHO software application, data analysis software, algorithm resource, sequence analysis software, software resource, data processing software Error correction algorithm designed for short-reads from next-generation sequencing platforms such as Illumina''s Genome Analyzer II. error correction, rnaseq, rna sequence, short-read, next-generation sequencing, ngs, illumina, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21482625
DOI:10.1101/gr.111351.110
Free, Available for download biotools:echo, OMICS_01102 https://bio.tools/echo, https://sources.debian.org/src/uc-echo/ SCR_011851 ECHO: A reference-free short-read error correction algorithm 2026-07-28 09:43:00 310
CANGS
 
Resource Report
Resource Website
1+ mentions
CANGS (RRID:SCR_011837) CANGS software application, software resource, data analysis software, data processing software A user-friendly utility for processing and analyzing 454 GS-FLX data in biodiversity studies. windows, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
PMID:20180949 biotools:cangs, OMICS_01084 https://bio.tools/cangs SCR_011837 2026-07-28 09:43:00 1
JiffyNet
 
Resource Report
Resource Website
1+ mentions
JiffyNet (RRID:SCR_011954) software application, service resource, data analysis service, software resource, production service resource, simulation software, analysis service resource Web based instant protein network modeler for newly sequenced species. Web server designed to instantly construct genome scale protein networks using protein sequence data. Provides network visualization, analysis pages and solution for instant network modeling of newly sequenced species. protein network, protein, network, genome, sequence, pathway annotation, network visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Yonsei University; Seoul; South Korea
National Research Foundation of Korea ;
Next-Generation BioGreen 21 Program
PMID:23685435 Free, Freely available OMICS_01548, biotools:jiffynet https://bio.tools/jiffynet SCR_011954 2026-07-28 09:42:58 1
sabre
 
Resource Report
Resource Website
100+ mentions
sabre (RRID:SCR_011843) sabre software application, software resource, data analysis software, data processing software Software tool to demultiplex barcoded reads into separate files. Works on both single-end and paired-end data in fastq format. Used in next generation sequencing to analyze a broad range of data. demultiplex, bardcode, separate, fastq, format, data, next, generation, sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:sabre, OMICS_01090 https://bio.tools/sabre SCR_011843 Systems Approach to Biomarker Research 2026-07-28 09:42:57 199
NGSmethDB
 
Resource Report
Resource Website
1+ mentions
NGSmethDB (RRID:SCR_012847) NGSmethDB service resource, data or information resource, data repository, database, storage service resource A dedicated database for the storage, browsing and data mining of whole-genome, single-base-pair resolution methylomes. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:20965971 OMICS_01844, biotools:ngsmethdb https://bio.tools/ngsmethdb SCR_012847 NGSmethDB - A database for NGS single-cytosine-resolution DNA methylation data 2026-07-28 09:43:11 9
TopHat
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
TopHat (RRID:SCR_013035) software application, data analysis software, sequence analysis software, software resource, data processing software, alignment software, image analysis software Software tool for fast and high throughput alignment of shotgun cDNA sequencing reads generated by transcriptomics technologies. Fast splice junction mapper for RNA-Seq reads. Aligns RNA-Seq reads to mammalian-sized genomes using ultra high-throughput short read aligner Bowtie, and then analyzes mapping results to identify splice junctions between exons.TopHat2 is accurate alignment of transcriptomes in presence of insertions, deletions and gene fusions. align, RNA-Seq, read, cDNA, sequencing, transcriptomics, fast, splice, junction, mapper, exon, analysis, bio.tools uses: Bowtie
is used by: CIRCexplorer
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: HISAT2
has parent organization: University of Maryland; Maryland; USA
has parent organization: University of California at Berkeley; Berkeley; USA
has parent organization: Johns Hopkins University; Maryland; USA
has parent organization: University of Washington; Seattle; USA
works with: GeneScissors
NHGRI R01 HG006102;
NHGRI R01 HG006677
PMID:23618408
PMID:19289445
DOI:10.1093/bioinformatics/btp120
Free, Available for download, Freely available biotools:tophat, OMICS_01257 https://github.com/infphilo/tophat, https://bio.tools/tophat, https://sources.debian.org/src/tophat/ http://tophat.cbcb.umd.edu/ SCR_013035 tophat, TopHat1, Tophat2 2026-07-28 09:43:10 9575
MitoBreak
 
Resource Report
Resource Website
10+ mentions
MitoBreak (RRID:SCR_012949) MitoBreak service resource, data or information resource, data repository, database, storage service resource Database with curated datasets of mitochondrial DNA (mtDNA) rearrangements. Users may submit new mtDNA rearrangements. mitochondrial dna rearrangement, mitochondrial dna, deletion, duplication, linear, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24170808 Free, The community can contribute to this resource biotools:mitobreak, OMICS_01640 https://bio.tools/mitobreak SCR_012949 2026-07-28 09:43:09 10
NGSEP
 
Resource Report
Resource Website
50+ mentions
NGSEP (RRID:SCR_012827) NGSEP software application, software resource, data analysis software, data processing software Software whose main functionality is the variants detector, which allows to make simultaneous discovery of SNVs, small indels, and CNVs.Accurate variant calling across species and sequencing protocols.Used for analysis of DNA high throughput sequencing data. matlab, variants detector, SNVs discovery, CNVs discovery, variant calling, species, sequencing protocols, bio.tools is listed by: bio.tools PMID:31099384 Free, Available for download, Freely available OMICS_00067, biotools:NGSEP https://bio.tools/NGSEP SCR_012827 NGSEP3, Next Generation Sequencing Eclipse Plugin, Next Generation Sequencing Experience Platform 2026-07-28 09:43:11 69
minfi
 
Resource Report
Resource Website
100+ mentions
minfi (RRID:SCR_012830) minfi software application, data analysis software, software resource, data processing software, data visualization software Software tools for analyzing and visualizing Illumina''s 450k array data. Illumina, array data, Analyze Illumina Infinium DNA methylation arrays, DNA methylation array, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: SWAN
has parent organization: Bioconductor
PMID:28035024 Free, Available for download, Freely available biotools:minfi, OMICS_00799, BioTools:minfi https://bio.tools/minfi, https://bio.tools/minfi, https://bio.tools/minfi SCR_012830 2026-07-28 09:43:18 390
affy
 
Resource Report
Resource Website
1000+ mentions
affy (RRID:SCR_012835) Affy software application, software resource, data analysis software, data processing software Software R package of functions and classes for the analysis of oligonucleotide arrays manufactured by Affymetrix. Used to process probe level data and for exploratory oligonucleotide array analysis. analysis, oligonucleotide, array, Affymetrix, process, probe, data, function, bio.tools is listed by: OMICtools
is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: affydata
is related to: R Project for Statistical Computing
is related to: OMICtools
Danish Biotechnology Instrument Center PMID:14960456 Free, Available for download, Freely available BioTools:affy, OMICS_00740, biotools:affy https://bio.tools/affy, https://sources.debian.org/src/r-bioc-affy/ SCR_012835 Affymetrix, analysis of Affymetrix GeneChip data at the probe level, analysis of Affymetrix GeneChip data 2026-07-28 09:43:18 2996
edgeR
 
Resource Report
Resource Website
10000+ mentions
edgeR (RRID:SCR_012802) edgeR software application, software resource, data analysis software, data processing software Bioconductor software package for Empirical analysis of Digital Gene Expression data in R. Used for differential expression analysis of RNA-seq and digital gene expression data with biological replication. empirical, analysis, digital, gene, expression, data, R, RNA-seq data, bio.tools is used by: Glimma
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: SARTools
is related to: Bioconductor
works with: tximport
NHMRC 406657;
Independent Research Institutes Infrastructure Support Scheme 361646;
Victorian State Government OIS grant ;
Melbourne International Research Scholarship ;
Harris and IBS Honours scholarships
PMID:19910308
DOI:10.1093/bioinformatics/btp616
Free, Available for download, Freely available OMICS_01308, biotools:edger https://bio.tools/edger, https://sources.debian.org/src/r-bioc-edger/ SCR_012802 edgeR, empirical analysis of digital gene expression data in R, Empirical analysis of Digital Gene Expression data in R 2026-07-28 09:43:10 21899
IMGT - the international ImMunoGeneTics information system
 
Resource Report
Resource Website
500+ mentions
IMGT - the international ImMunoGeneTics information system (RRID:SCR_012780) IMGT service resource, data or information resource, data analysis service, database, production service resource, analysis service resource, topical portal, portal A high-quality integrated knowledge resource specialized in the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility complex (MHC) of human and other vertebrate species, and in the immunoglobulin superfamily (IgSF), MHC superfamily (MhcSF) and related proteins of the immune system (RPI) of vertebrates and invertebrates, serving as the global reference in immunogenetics and immunoinformatics. IMGT provides a common access to sequence, genome and structure Immunogenetics data, based on the concepts of IMGT-ONTOLOGY and on the IMGT Scientific chart rules. IMGT works in close collaboration with EBI (Europe), DDBJ (Japan) and NCBI (USA). IMGT consists of sequence databases, genome database, structure database, and monoclonal antibodies database, Web resources and interactive tools. immunogenetics, immunoinformatics, immunoglobulin, antibody, t cell receptor, major histocompatibility complex, immunoglobulin superfamily, major histocompatibility complex superfamily, protein, immune system, sequence, genome, structure, monoclonal antibody, gold standard, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: IMGT Repertoire
has parent organization: Montpellier 2 University; Montpellier; France
is parent organization of: IMGT/LIGM-DB
is parent organization of: IMGT/GENE-DB
is parent organization of: IMGT-ONTOLOGY
is parent organization of: IMGT/V-QUEST
is parent organization of: IMGT/HLA
CNRS ;
MESR ;
Reseau National des Genopoles ;
Region Languedoc-Roussillon ;
European Union BIOMED1 BIOCT930038;
European Union Biotechnology BIOTECH2 BIO4CT960037;
European Union 5th PCRDT Quality of Life and Management of Living Resources QLG2-2000-01287;
Agence Nationale de la recherche ANR BIOSYS06_135457;
EU ImmunoGrid IST-028069
PMID:18978023 nif-0000-03011, biotools:imgt https://bio.tools/imgt http://imgt.cines.fr SCR_012780 ImMunoGeneTics Information System, IMGT/LIGM, ImMunoGeneTics 2026-07-28 09:43:17 746
GeneSigDB
 
Resource Report
Resource Website
10+ mentions
GeneSigDB (RRID:SCR_013275) GeneSigDB service resource, data or information resource, data repository, data analysis service, storage service resource, data access protocol, software resource, database, production service resource, web service, analysis service resource Database of traceable, standardized, annotated gene signatures which have been manually curated from publications that are indexed in PubMed. The Advanced Gene Search will perform a One-tailed Fisher Exact Test (which is equivalent to Hypergeometric Distribution) to test if your gene list is over-represented in any gene signature in GeneSigDB. Gene expression studies typically result in a list of genes (gene signature) which reflect the many biological pathways that are concurrently active. We have created a Gene Signature Data Base (GeneSigDB) of published gene expression signatures or gene sets which we have manually extracted from published literature. GeneSigDB was creating following a thorough search of PubMed using defined set of cancer gene signature search terms. We would be delighted to accept or update your gene signature. Please fill out the form as best you can. We will contact you when we get it and will be happy to work with you to ensure we accurately report your signature. GeneSigDB is capable of providing its functionality through a Java RESTful web service. gene, gene signature, curated gene signature, gene expression, gene expression signature, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Dana-Farber Cancer Institute
has parent organization: Computational Biology and Functional Genomics Laboratory at Harvard
Cancer Genome Research Institute ;
Dana-Farber Cancer Institute ;
Women's Cancers Program ;
Claudia Adams Barr Foundation ;
NLM 1R01 LM010129;
NCI 1U19 CA148065;
NHGRI 1P50 HG004233
PMID:22110038 biotools:genesigdb, nlx_149342 https://bio.tools/genesigdb SCR_013275 Gene Signature Data Base, GeneSigDB - Curated Gene Signatures Database 2026-07-28 09:43:12 24

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