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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Protein Databank Fun
 
Resource Report
Resource Website
1+ mentions
Protein Databank Fun (RRID:SCR_008226) software application, software resource, data analysis software, data processing software THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. PDBfun is a web server for structural and functional analysis of proteins at the residue level. pdbFun gives fast access to the whole Protein Data Bank (PDB) organized as a database of annotated residues. The available data (features) range from solvent exposure to ligand binding ability, location in a protein cavity, secondary structure, residue type, sequence functional pattern, protein domain and catalytic activity. PDBfun is an integrated web tool for querying the PDB at the residue level and for local structural comparison. It integrates knowledge on single residues in protein structures coming from other databases or calculated with available or in-house developed instruments for structural analysis. Each set of different annotations represents a feature. Features are listed in PDBfun main page in orange. Features can be used for building residues selections. functional, 2d, ability, activity, analysis, binding, catalytic, cavity, chain, cleft, domain, ligand, location, motif, protein, protein structure databases, residue, secondary, sequence, size, solvent, structural, structure, surface THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-21315 SCR_008226 PDBfun 2026-07-28 09:42:18 2
GMAP
 
Resource Report
Resource Website
500+ mentions
GMAP (RRID:SCR_008992) GMAP software application, source code, software resource, data processing software, alignment software, image analysis software THIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. A software program for mapping and aligning cDNA sequences to a genome. The program maps and aligns a single sequence with minimal startup time and memory requirements, and provides fast batch processing of large sequence sets. The program generates accurate gene structures, even in the presence of substantial polymorphisms and sequence errors, without using probabilistic splice site models. Methodology underlying the program includes a minimal sampling strategy for genomic mapping, oligomer chaining for approximate alignment, sandwich DP for splice site detection, and microexon identification with statistical significance testing. mrna, est sequence, expressed sequence tag, sequence, cdna sequence, genome, cdna, bio.tools is used by: deFuse
is listed by: Debian
is listed by: bio.tools
has parent organization: Genentech
PMID:15728110 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_15072, biotools:gmap, nlx_152505 https://bio.tools/gmap, https://sources.debian.org/src/gmap/ SCR_008992 2026-07-28 09:42:16 594
CMAP
 
Resource Report
Resource Website
100+ mentions
CMAP (RRID:SCR_009034) CMap software application, data analysis software, software resource, data processing software Web-based tool that allows users to view comparisons of genetic and physical maps. The package also includes tools for curating map data. (entry from Genetic Analysis Software) gene, genetic, genomic, perl, unix, solaris, freebsd, linux, sequence, FASEB list is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: SoftCite
has parent organization: Generic Model Organism Database Project
works with: Drug Gene Budger
PMID:19648141 GNU General Public License nlx_153998, OMICS_00933 https://sourceforge.net/projects/gmod/files/cmap/ http://www.gmod.org/cmap/, http://gmod.org/wiki/Cmap SCR_009034 , GMOD Comparative Mapping (CMap) tool, Comparative Mapping tool, genetic and comparative maps 2026-07-28 09:42:19 413
LAST
 
Resource Report
Resource Website
100+ mentions
LAST (RRID:SCR_006119) LAST software application, service resource, data analysis service, software resource, data processing software, production service resource, analysis service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for aligning sequences, similar to BLAST 2 sequences that colour-codes the alignments by reliability. Another useful feature of LAST is that it can compare huge (vertebrate-genome-sized) datasets. Unfortunately, this only applies to the downloadable version of LAST, not the web service. The web service can just about handle bacterial genomes, but it will take a few minutes and the output will be large. LAST can: * Handle big sequence data, e.g: ** Compare two vertebrate genomes ** Align billions of DNA reads to a genome * Indicate the reliability of each aligned column. * Use sequence quality data properly. * Compare DNA to proteins, with frameshifts. * Compare PSSMs to sequences * Calculate the likelihood of chance similarities between random sequences. LAST cannot (yet): * Do spliced alignment., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence alignment, align, vertebrate, genome, sequence, alignment, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: RecountDB
has parent organization: National Institute of Advanced Industrial Science and Technology
National Genome Research Network ;
INTEuropean Union Systems Institute ;
Japanese Ministry of Education Culture Sports Science and Technology MEXT
PMID:21209072
PMID:20144198
PMID:20110255
DOI:10.1093/nar/gkq010
THIS RESOURCE IS NO LONGER IN SERVICE nlx_151594, biotools:last, OMICS_15813 https://bio.tools/last, https://sources.debian.org/src/last-align/ SCR_006119 2026-07-28 09:41:31 397
FASTA
 
Resource Report
Resource Website
500+ mentions
FASTA (RRID:SCR_011819) FASTA software application, data analysis software, sequence analysis software, software resource, data processing software Software package for DNA and protein sequence alignment to find regions of local or global similarity between Protein or DNA sequences, either by searching Protein or DNA databases, or by identifying local duplications within a sequence. sequence, alignment, DNA, protein, similarity, searching is listed by: OMICtools
is listed by: SoftCite
has parent organization: European Bioinformatics Institute
Free, Freely available OMICS_00994 SCR_011819 Federal Acquisition STreamlining Act 2026-07-28 09:43:00 845
StringTie
 
Resource Report
Resource Website
1000+ mentions
StringTie (RRID:SCR_016323) software application, data analysis software, sequence analysis software, software resource, data processing software Software application for assembling of RNA-Seq alignments into potential transcripts. It enables improved reconstruction of a transcriptome from RNA-seq reads. This transcript assembling and quantification program is implemented in C++ . assembling, RNA, sequence, transcript, gene, alignment, reconstruction, read, analysis, process, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
the Cancer Prevention and Research Institute of Texas ;
NHGRI R01 HG006677;
NIGMS R01 GM105705;
NHGRI R01 HG006102;
NCI R01 CA120185;
NCI R01 CA134292
PMID:25690850
DOI:10.1038/nbt.3122
Open source, Free, Freely available, Available for download biotools:stringtie, OMICS_07226 https://github.com/gpertea/stringtie, https://bio.tools/stringtie, https://sources.debian.org/src/stringtie/ SCR_016323 2026-07-28 09:44:16 4072
Hinge
 
Resource Report
Resource Website
1+ mentions
Hinge (RRID:SCR_016135) software application, data analysis software, sequence analysis software, software resource, data processing software Software application for long read genome assembly based on hinging. Used in long-read sequencing technologies in genome assemblies to achieve optimal repeat resolution. long, read, genome, assembly, hinging, sequence, optimal, repeat, resolution is listed by: Debian
is listed by: OMICtools
PMID:28320918 Free, Available for download OMICS_12339 https://sources.debian.org/src/hinge/ SCR_016135 2026-07-28 09:44:06 9
FreeContact
 
Resource Report
Resource Website
10+ mentions
FreeContact (RRID:SCR_016113) software application, software resource, data processing software, alignment software, image analysis software Alignment software for large-scale protein contact or protein-protein interaction prediction optimized for speed through shorter runtimes. FreeContact provides the opportunity to compute contact predictions in any environment (desktop or cloud). protein, structure, prediction, sequence, analysis, fast, contact, alignment, multiple is listed by: OMICtools
is related to: Debian
Alexander von Humboldt Foundation ;
German Ministry for Research and Education (BMBF: Bundesministerium fuer Bildung und Forschung) ;
Research Council of Norway 208481
PMID:24669753
DOI:10.1186/1471-2105-15-85
Open source, Free, Available for download OMICS_03520 https://rostlab.org/owiki/index.php/FreeContact, https://sources.debian.org/src/libfreecontact-perl/ SCR_016113 2026-07-28 09:44:09 21
QModeling
 
Resource Report
Resource Website
1+ mentions
QModeling (RRID:SCR_016358) software application, image analysis software, data analysis software, software resource, data processing software, software toolkit Software toolbox for Statistical Parametric Mapping (SPM) to fit reference-region kinetic models (SRTM, SRTM2, Patlak Reference and Logan Reference Plot) are currently available in QModeling to dynamic PET studies. Used for the analysis of brain imaging data sequences. statistical, parametric, mapping, reference, region, kinetic, model, dynamic, analysis, brain, data, imaging, sequence is related to: University of Malaga; Andalusia; Spain
is related to: MATLAB
DOI:10.1007/s12021-018-9384-y Free, Available for download, Available after registration SCR_016358 2026-07-28 09:44:12 1
ClonalOrigin
 
Resource Report
Resource Website
1+ mentions
ClonalOrigin (RRID:SCR_016061) software application, data analysis software, sequence analysis software, software resource, data processing software Software package for comparative analysis of the sequences of a sample of bacterial genomes in order to reconstruct the recombination events that have taken place in their ancestry. comparative, analysis, sequence, bacteria, genome, reconstruct, recombination, events, ancestry, bayesian is listed by: Debian
is listed by: OMICtools
is related to: Imperial College London; London; United Kingdom
is related to: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust WT082930MA;
National Science Foundation DBI-0630765;
Science Foundation of Ireland 05/FE1/B882
PMID:20923983
DOI:10.1534/genetics.110.120121
Free, Available for download OMICS_18881 https://sources.debian.org/src/clonalorigin/ SCR_016061 2026-07-28 09:44:08 8
PseudoFuN
 
Resource Report
Resource Website
1+ mentions
PseudoFuN (RRID:SCR_017095) service resource, data or information resource, data analysis service, database, production service resource, analysis service resource Software as database and query tool for homologous pseudogene and coding gene families. Collection of human pseudogenes and gene associations. Supports search, graphical visualization and functional analysis of pseudogenes and coding genes based on PGG families. gene, pseudogene, sequence, homology, regulatory, network, miRNA, coexpression, noncoding, RNA, TCGA, cancer has parent organization: Ohio State University; Ohio; USA
has parent organization: Indiana University School of Medicine; Indiana; USA
NLM T15 LM011270 Free, Freely available https://github.com/yanzhanglab/PseudoFuN_app SCR_017095 Pseudogene Functional Networks 2026-07-28 09:44:29 2
SMARTdenovo
 
Resource Report
Resource Website
100+ mentions
SMARTdenovo (RRID:SCR_017622) software application, software resource, data processing software, alignment software, image analysis software Software tool as de novo assembler for PacBio and Oxford Nanopore data. It produces assembly from all-vs-all raw read alignments without error correction stage. Allows to read overlapping, rescue missing overlaps, identify low-quality regions and chimaera and produce better consensus. De novo, assembler, PacBio, Oxford Nanopore, data, sequence, raw, read, alignment, error, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available BioTools:SMARTdenovo, biotools:SMARtdenovo https://bio.tools/SMARTdenovo, https://bio.tools/SMARTdenovo, https://bio.tools/SMARTdenovo SCR_017622 2026-07-28 09:44:35 159
duphold
 
Resource Report
Resource Website
1+ mentions
duphold (RRID:SCR_016938) software application, software resource, data analysis software, data processing software Software tool to annotate structural variant calls with sequence depth information that can add or remove confidence to SV predicted to affect copy number. Indicates the presence of a rapid change in depth relative to the regions surrounding the breakpoints. Allows the run time to be nearly independent of the number of variants important for large, jointly called projects with many samples. Annotates structural variant predictions made from both short read and long read data. annotate, structural, variation, call, sequence, depth, confidence, predict, copy, number, short, long, read, data is listed by: OMICtools Free, Available for download, Freely available SCR_016938 2026-07-28 09:44:25 2
OGDraw
 
Resource Report
Resource Website
100+ mentions
OGDraw (RRID:SCR_017337) OGDRAW software application, service resource, software resource, data processing software, data visualization software, software toolkit Software package for graphical visualization of organellar genomes. Converts annotations in GenBank format into graphical maps. Used to create visual representations of circular and linear annotated genome sequences provided as GenBank files or accession numbers. graphical, visualization, organellar, genome, convert, annotation, GenBank, format, map, DNA, sequence works with: GenBank Max Planck Society PMID:30949694 Free, Freely available SCR_017337 Draw Organelle Genome Maps, OrganellarGenomeDRAW 2026-07-28 09:44:33 214
NanoPipe
 
Resource Report
Resource Website
1+ mentions
NanoPipe (RRID:SCR_016852) NanoPipe service resource, data analysis service, data access protocol, software resource, production service resource, web service, analysis service resource Web tool for analysis of MinION (ONT) long sequencing reads. Used for analysis of reads generated by the Oxford Nanopore sequencing devices. Provides alignments to any target of interest, alignment statistics and information about polymorphisms. analysis, MinION, long, sequence, read, Oxford Nanopore, alignment, target, statistics, polymorphism, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Muenster; Muenster; Germany
Institute of Bioinformatics Muenster ;
Germany
PMID:30689855 Free, Available for download, Freely Available biotools:NanoPipe https://github.com/IOB-Muenster/nanopipe2, https://bio.tools/NanoPipe SCR_016852 NanoPipe, nanopipe2 2026-07-28 09:44:25 5
DETONATE
 
Resource Report
Resource Website
1+ mentions
DETONATE (RRID:SCR_017035) DETONATE software application, data analysis software, sequence analysis software, software resource, data processing software Software tool to evaluate de novo transcriptome assemblies from RNA-Seq data. Consists of RSEM-EVAL and REF-EVAL packages. RSEM-EVAL is reference-free evaluation method. REF-EVAL is reference based and can be used to compare sets of any kinds of genomic sequences. evaluate, de novo, transcriptome, assembly, RNAseq, data, RSEM-EVAL, REF-EVAL, dataset, genomic, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Wisconsin-Madison; Wisconsin; USA
NHGRI R01 HG005232;
NLM T15 LM007359
PMID:25608678 Free, Available for download, Freely available biotools:detonate https://bio.tools/detonate SCR_017035 DE novo TranscriptOme rNa-seq Assembly with or without the Truth Evaluation, DETONATE 2026-07-28 09:44:30 2
A plasmid Editor
 
Resource Report
Resource Website
50+ mentions
A plasmid Editor (RRID:SCR_014266) ApE software application, data analysis software, sequence analysis software, software resource, data processing software, standalone software Software tool for plasmid and sequence editing, annotating and drawing plasmid sequences. Used to view circular or linear maps of DNA sequences. Users can perform virtual digests whereby they select predefined DNA ladder, or specify their own, and visualize theoretical DNA fragments. Used to highlight restriction sites in editing window, accurately reflect Dam/Dcm blocking of enzyme sites, highlighting and drawing graphic maps using feature annotations from genbank and embl files, highlighting text using pre-defined and custom feature libraries, and directly BLASTing selected sequence at NCBI or Wormbase. Runs across Windows, OS X, and Linux/Unix. Plasmid, editing, sequence, annotating, drawing, restriction, site, enzyme, map, DNA, fragment works with: GenBank
works with: NCBI
works with: WormBase
Free, Available for download, Freely available https://jorgensen.biology.utah.edu/wayned/ape/ http://ape-a-plasmid-editor.wikispaces.com SCR_014266 A plasmid Editor 2026-07-28 09:43:23 93
Hypermut
 
Resource Report
Resource Website
100+ mentions
Hypermut (RRID:SCR_014933) software application, web application, data analysis software, sequence analysis software, software resource, data processing software Web application for the analysis and detection of APOBEC-induced hypermutations. The first sequence in the input alignment will be used as the reference sequence, and each of the other sequences will be used as a query sequence. mutation, hypermutation, sequence, sequence analysis software genome, web application PMID:10869039 SCR_014933 Hypermut 2.0 2026-07-28 09:43:56 124
Bowtie 2
 
Resource Report
Resource Website
1000+ mentions
Bowtie 2 (RRID:SCR_016368) software application, data analysis software, sequence analysis software, software resource, data processing software, alignment software, image analysis software Ultrafast and memory efficient tool for aligning sequencing reads to long reference sequences. Supports gapped, local, and paired end alignment modes. More suited to finding longer, gapped alignments in comparison with original Bowtie method. sequence, analysis, long, reference, sequence, read, alignment, gap, local, pair, end, rna, rnaseq, bio.tools is used by: HLA-HD
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Bowtie
NHGRI R01 HG006102;
NIGMS R01 GM083873
PMID:22388286 Free, Available for download, Freely available biotools:bowtie2 http://bowtie-bio.sourceforge.net/bowtie2/index.shtml, https://github.com/BenLangmead/bowtie2, https://bio.tools/bowtie2 SCR_016368 , bowtie 2, bowtie2 v 2.2.3 2026-07-28 09:43:31 1745
CESG
 
Resource Report
Resource Website
1+ mentions
CESG (RRID:SCR_008451) CESG data or information resource, organization portal, portal It is a specialized research center supported by the Protein Structure Initiative (PSI) of the National Institute of General Medical Sciences (NIGMS), one of the National Institutes of Health (NIH). PSI is a federal, university, and industry effort aimed at dramatically reducing the costs and lessening the time it takes to determine a three-dimensional protein structure. The long-range goal of PSI is to solve 10,000 protein structures in 10 years and to make the three-dimensional atomic-level structures of most proteins easily obtainable from knowledge of their corresponding DNA sequences. CESG is located within the Department of Biochemistry at the University of Wisconsin-Madison (Madison, WI) and the Department of Biochemistry at the Medical College of Wisconsin (Milwaukee, WI). CESG develops new methods and technologies to address unique eukaryotic bottlenecks and disseminates its methodologies and experimental results to the scientific community worldwide through: :- Cell-Free Protein Production Workshops :- Plasmids at PSI Materials Repository :- Posters Presented at Scientific Meetings :- Publications in PubMed / PubMed Central :- Sesame (LIMS) Available for Researchers :- Solved Structures in the Protein Data Bank :- Technology Dissemination Reports They have welcomed requests by researchers to solve eukaryotic protein structures, particularly medically relevant proteins, through our Online Structure Request System for Researchers. They have solved many community-nominated targets and deposited information about these targets in public databases and published on our investigations and findings. Sponsors: CESG is supported by NIH / NIGMS Protein Structure Initiative grant numbers U54 GM074901 and P50 GM064598. eukaryotic, structural, genomics, research, center, protein, structure, medical, science, health, atom, dna, sequence, knowledge, biochemistry, technology, cell, plasmid has parent organization: University of Wisconsin-Madison; Wisconsin; USA nif-0000-30322 SCR_008451 Center for Eukaryotic Structural Genomics, The Center for Eukaryotic Structural Genomics 2026-07-28 09:42:09 9

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