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http://contra.stanford.edu/contrafold/

Software novel secondary structure prediction method based on conditional log-linear models, a flexible class of probabilistic models which generalize upon SCFGs by using discriminative training and feature-rich scoring. Used for sequence prediction.

Proper citation: CONTRAfold (RRID:SCR_023994) Copy   

•   Source: SciCrunch Registry

https://biocore.github.io/emperor/

Web browser enabled tool with versatile command line interface to perform exploratory investigations of 3D visualizations of microbial community data, such as principal coordinates plots. EMPeror includes set of controllers to modify features as function of metadata. Web interactive next generation tool for analysis, visualization and understanding of high throughput microbial ecology datasets.

Proper citation: EMPeror (RRID:SCR_024013) Copy   

•   Source: SciCrunch Registry

https://embossgui.sourceforge.net/

Web based graphical user interface to the EMBOSS suite of bioinformatics tools.

Proper citation: EMBOSS explorer (RRID:SCR_024014) Copy   

•   Source: SciCrunch Registry

https://github.com/rrwick/Filtlong

Software tool for filtering long reads by quality.Can take set of long reads and produce smaller, better subset. Uses both read length and read identity when choosing which reads pass the filter.

Proper citation: Filtlong (RRID:SCR_024020) Copy   

•   Source: SciCrunch Registry

https://rostlab.org/owiki/index.php/Metastudent

Software tool to predict gene ontology terms for protein sequences through homology.

Proper citation: Metastudent (RRID:SCR_024110) Copy   

•   Source: SciCrunch Registry

http://www.ctsim.org

Software tool to simulate process of transmitting X-rays through phantom objects. Reconstructs original phantom image from projections. Has wide array of image analysis and image processing functions.

Proper citation: CTSim (RRID:SCR_024004) Copy   

•   Source: SciCrunch Registry

https://github.com/dmnfarrell/epitopepredict

Open source software tool as programmatic framework and command line tool designed to aid process of MHC binding prediction. Provides access to multiple binding prediction algorithms under single interface and scales for whole genomes using multiple target MHC alleles.Software should be run on Linux operating system. Ubuntu is recommended but most major distributions will be fine. Windows is not supported.

Proper citation: epitopepredict (RRID:SCR_019221) Copy   

•   Source: SciCrunch Registry

https://run.biosimulations.org

Web tool for executing broad range of modeling studies and visualizing their results. Provides web interface for reusing any model. Models, simulations, and visualizations are available under licenses specified for each resource.

Proper citation: runBioSimulations (RRID:SCR_019110) Copy   

•   Source: SciCrunch Registry

https://biosimulators.org

Web tool as collection of containerized biosimulation tools that provide consistent interfaces and guide to choosing simulator. Helps to find simulation tools that have capabilities, including supported modeling frameworks, simulation algorithms, and modeling formats, needed for specific modeling projects.

Proper citation: BioSimulators (RRID:SCR_019111) Copy   

•   Source: SciCrunch Registry

https://jtremblay.github.io/amplicontagger.html

Software tool as rRNA marker gene amplicon pipeline coded in python framework that enables fine tuning and integration of virtually any potential rRNA gene amplicon bioinformatic procedure. Designed to work within HPC environment, supporting complex network of job dependencies with smart restart mechanism in case of job failure or parameter modifications.

Proper citation: AmpliconTagger (RRID:SCR_019112) Copy   

•   Source: SciCrunch Registry

http://metagenomics.iiserb.ac.in/mp3/

Software tool for prediction of pathogenic proteins in genomic and metagenomic data. Used for identification of partial pathogenic proteins predicted from short (100-150 bp) metagenomic reads and also performs on complete protein sequences., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: MP3 tool (RRID:SCR_019282) Copy   

•   Source: SciCrunch Registry

https://github.com/esctrionsit/snphub

Web Shiny-based server framework for retrieving, analyzing and visualizing large genomic variations data.

Proper citation: SnpHub (RRID:SCR_018177) Copy   

•   Source: SciCrunch Registry

https://github.com/WangHYLab/fcirc

Software Python pipeline for linear and circular RNAs of known fusions exploration. Pipeline for exploring linear transcripts and circRNAs of known fusions based on RNA-Seq data. Known fusion genes are from multiple databases like COSMIC, ChimerDB, TicDB, FARE-CAFE and FusionCancer or user-added gene-pairs.

Proper citation: Fcirc (RRID:SCR_018090) Copy   

•   Source: SciCrunch Registry

https://github.com/bcgsc/NanoSim

Software tool as Nanopore sequence read simulator based on statistical characterization. Oxford Nanopore Technology sequence simulator written in Python and R. Benefits development of scalable next generation sequencing technologies for long nanopore reads, including genome assembly, mutation detection, and metagenomic analysis software.

Proper citation: NanoSim (RRID:SCR_018243) Copy   

•   Source: SciCrunch Registry

https://www.biosimulations.org/

Web tool for sharing and re-using biomodels, simulations, and visualizations of simulations results. Supports variety of modeling frameworks including kinetic, constraint based, and logical modeling, model formats including BNGL, CellML, SBML, and simulation tools including COPASI, libRoadRunner/tellurium, NFSim, VCell.

Proper citation: BioSimulations (RRID:SCR_018733) Copy   

•   Source: SciCrunch Registry

https://dogma.ccbb.utexas.edu/

Web-based annotation tool for plant chloroplasts and animal mitochondrial genomes. DOGMA allows the use of BLAST searches against a custom database, and conservation of basepairing in the secondary structure of animal mitochondrial tRNAs to identify and annotate genes.

Proper citation: DOGMA (RRID:SCR_015060) Copy   

•   Source: SciCrunch Registry

http://floresta.eead.csic.es/primers4clades

Web application for the design of PCR primers for cross-species amplification of novel sequences from metagenomic DNA or from uncharacterized organisms belonging to user-specified phylogenetic lineages. It implements an extended CODEHOP strategy and evaluates thermodynamic properties of the oligonucleotide pairs.

Proper citation: primers4clades (RRID:SCR_015714) Copy   

•   Source: SciCrunch Registry

http://abacus.gene.ucl.ac.uk/software/indelible/

Software that generates nucleotide, amino acid and codon sequence data by simulating insertions and deletions (indels) as well as substitutions. It is used for biological sequence simulation of multi-partitioned nucleotide, amino-acid, or codon data sets through the processes of insertion, deletion, and substitution in continuous time.

Proper citation: Indelible (RRID:SCR_016163) Copy   

•   Source: SciCrunch Registry

https://bitbucket.org/nsegata/graphlan/wiki/Home

Software tool for producing high-quality circular representations of taxonomic and phylogenetic trees. Used for concise, integrative, informative, and publication-ready representations of phylogenetically- and taxonomically-driven investigation as a high-resolution microbial tree of life with taxonomic annotations., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: GraPhlAn (RRID:SCR_016130) Copy   

•   Source: SciCrunch Registry

https://nmrprocflow.org

Software as graphical and interactive tool dedicated to 1D spectra processing for NMR-based metabolomics.

Proper citation: NMRProcFlow (RRID:SCR_016592) Copy   

•   Source: SciCrunch Registry